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Clinical Trial
. 1998 Nov;15(10):579-82.
doi: 10.1023/a:1020373009043.

A matched study to determine whether low-dose aspirin without heparin improves pregnancy rates following frozen embryo transfer and/or affects endometrial sonographic parameters

J H Check  1 , C Dietterich, D Lurie, A Nazari, J Chuong
Affiliations
Clinical Trial

A matched study to determine whether low-dose aspirin without heparin improves pregnancy rates following frozen embryo transfer and/or affects endometrial sonographic parameters

J H Check et al. J Assist Reprod Genet. 1998 Nov.

Abstract

Purpose: The objective of the matched, controlled study was to determine whether low-dose aspirin therapy without heparin improves pregnancy rates following frozen embryo transfer.

Methods: Thirty-six women who did not achieve a pregnancy following fresh embryo transfer and who had frozen embryos available for another transfer were included. Eighteen women were treated with 81 mg aspirin from day 2 of the cycle through pregnancy testing. If the beta-human chorionic gonadotropin level was positive, aspirin was continued through the pregnancy. Eighteen women were not given aspirin. The mean outcome variables were pregnancy and implantation rates.

Results: The clinical pregnancy rate in the aspirin group was 11.1%, compared with 33.3% for the controls, and implantation rates were 2.9 and 10.9%, respectively.

Conclusions: No positive effects of low-dose aspirin therapy on pregnancy rates following frozen embryo transfer were observed.

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References

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