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. 1976 Jun;3(6):1487-98.
doi: 10.1093/nar/3.6.1487.

Globin mRNA contains a sequence complementary to double-stranded region of nuclear pre-mRNA

A P Ryskov, O V Tokarskaya, G P Georgiev, C Coutelle, B Thiele
Free PMC article

Globin mRNA contains a sequence complementary to double-stranded region of nuclear pre-mRNA

A P Ryskov et al. Nucleic Acids Res. 1976 Jun.
Free PMC article

Abstract

Melted ds RNA isolated from rabbit bone marrow pre-mRNA was hybridized with excess of globin mRNA which was prepared from rabbit reticulocytes. 7-9% of ds sequences became RNAase-stable and about 30% of the sequences could be bound to poly(U)-Sepharose through poly (A) of mRNA. The size of RNAase-stable hybrid is about 30 nucleotides, that is one fourth of the length of one strand of the ds RNA.

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References

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