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. 1998 Apr 7;8(7):775-80.
doi: 10.1016/s0960-894x(98)00104-8.

Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors

J V Duncia  1 , J B Santella 3rd, C A Higley, M K VanAtten, P C Weber, R S Alexander, C A Kettner, J R Pruitt, A Y Liauw, M L Quan, R M Knabb, R R Wexler
Affiliations

Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors

J V Duncia et al. Bioorg Med Chem Lett. .

Abstract

Substituted pyrazoles, 1,2,4-triazoles, and tetrazoles are good surrogates for cis-amide bonds in a series of boronate ester thrombin inhibitors.

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