Infrared studies of protein-induced perturbation of lipids in lipoproteins and membranes
- PMID: 9871982
- DOI: 10.1016/s0009-3084(98)00080-2
Infrared studies of protein-induced perturbation of lipids in lipoproteins and membranes
Abstract
The paper reviews the main recent publications concerning infrared (IR) spectroscopy as applied to the study of lipid-protein interactions in model and cell membranes, lipoproteins, and related systems (e.g. lung surfactant). The review focuses mainly on transmission IR. Based on the available data, a number of general conclusions are presented on the perturbations caused by proteins on either the hydrocarbon chains, the polar headgroups or the interface region. Lipid-protein interactions in native cell membranes do not reveal significant differences from what is observed in semisynthetic model systems.
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