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Clinical Trial
. 1998 Dec 15;82(12):1555-7, A8.
doi: 10.1016/s0002-9149(98)00708-5.

Effect of long-term estrogen therapy on brachial arterial endothelium-dependent vasodilation in women with Raynaud's phenomenon secondary to systemic sclerosis

J Lekakis  1 , C Papamichael, M Mavrikakis, A Voutsas, S Stamatelopoulos
Affiliations
Clinical Trial

Effect of long-term estrogen therapy on brachial arterial endothelium-dependent vasodilation in women with Raynaud's phenomenon secondary to systemic sclerosis

J Lekakis et al. Am J Cardiol. .

Abstract

Endothelium-dependent and endothelium-independent dilation were reduced in patients with Raynaud's phenomenon secondary to systemic sclerosis. Conjugated estrogen given for 4 weeks significantly improved endothelial function compared with placebo.

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