[Immuno-electro-diffusion on cellulose acetate membrane for serological testing in human malaria (author's transl)]
- PMID: 98748
[Immuno-electro-diffusion on cellulose acetate membrane for serological testing in human malaria (author's transl)]
Abstract
An immuno-electro-diffusion assay for human malaria, using cellulose acetate gel, is described. More than 3500 sera have been tested by this method, which proved very useful for epidemiology since 400 sera a day can be tested by one person, with simple equipment. Its sensitivity compared well to the IFA test, although the antibodies revealed are quite different. A constnat precipitin line appeared, against 56 degrees C labile antigens, in sera of subjects infected by P. falciparum, and up to 8 other precipitins per serum tested. The test may be useful in analyzing these multiple antibodies occurring in patients with malaria.