Differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions
- PMID: 98814
Item in Clipboard
Differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions
Rev Bras Pesqui Med Biol.
1978 Jun.
Abstract
Guinea pigs were sensitized with heat killed M. tuberculosis, M. kansasii, M. scrofulaceum, and M. avium-intracellulare. Purified Protein Derivatives (PPDs) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. The homologous reactions were consistently more intense than heterologous reactions in all three procedures. The skin test procedure was more sensitive than either in vitro method. Positive skin test reactions were elicited with 2 times and 50 times less antigen than, respectively, the lymphocyte transformation and the macrophage migration tests.
Similar articles
-
Induction kinetics of delayed hypersensitivity towards Mycobacterium tuberculosis and M. avium: analysis of cross-reactions elicited by PPD-tuberculin and PPD-B.Rev Bras Pesqui Med Biol. 1978 Dec;11(6):313-9. Rev Bras Pesqui Med Biol. 1978. PMID: 108772 No abstract available.
-
Species-specific antigenic Mycobacterium tuberculosis proteins tested by delayed-type hypersensitivity response.Int J Tuberc Lung Dis. 2010 Apr;14(4):489-94. Int J Tuberc Lung Dis. 2010. PMID: 20202308
-
Specificity of purified protein derivative extracts from cultures of mycobacteria killed by phenol.Res Vet Sci. 1981 Nov;31(3):284-8. Res Vet Sci. 1981. PMID: 7342222
-
Survey of recent studies on mechanism and significance of delayed (cellular)-type hypersensitivity.Ann Immunol Hung. 1972;16(0):191-8. Ann Immunol Hung. 1972. PMID: 4137958 Review. No abstract available.
-
Cell migration inhibition: an appraisal.Acta Allergol. 1974 Jun;29(3):185-208. doi: 10.1111/j.1398-9995.1974.tb01648.x. Acta Allergol. 1974. PMID: 4277394 Review. No abstract available.