Case Reports
doi: 10.1007/BF01405861.
Intrathecal pharmacotherapy in coma
- PMID: 989256
- DOI: 10.1007/BF01405861
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Case Reports
Intrathecal pharmacotherapy in coma
Acta Neurochir (Wien).
1976.
Abstract
A study was made of intrathecal infusion as a route for administration of drugs for the CNS. We recognize the presence of blood brain and CSF brain barriers. CDP-choline was used as the brain activator, and the effect of the intrathecally infused drug was investigated clinically. Fifteen patients with disturbances of consciousness due to primary cerebral lesions received a total of 39 intrathecal infusions of CDP-choline, and were examined neurologically and electroencephalographically before and after treatment.
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