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. 1998;14(10):886-7.
doi: 10.1093/bioinformatics/14.10.886.

HIV-1 genotypic resistance: automated sequence analysis and interpretation

C P Goujon  1 , V M Schneider, C Jacomet, J C Nicolas
Affiliations

HIV-1 genotypic resistance: automated sequence analysis and interpretation

C P Goujon et al. Bioinformatics. 1998.

Abstract

We present here GRANT ( G enotypic R esistance An alysis T ool), a program that automatically detects resistance-related mutations in HIV-1 protein sequences, and comments on the degree of resistance conferred when possible. This program is easily user-customizable, allowing immediate updates as new resistance mutations are discovered, or use with an organism other than HIV.

Availability: The package is available free of charge over the internet, either directly from the authors, or by anonymous ftp (ftp. infobiogen.fr/pub/logiciels/mac/biology or windows as appropriate). Versions exist for PPC and 68K Apple Macintosh running MacOS 7.5 or higher. Microsoft Excel 5.0 is required for quality output. A PC version is in progress.

Contact: goujon@infobiogen.fr

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