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. 1998 Dec 11:865:290-6.
doi: 10.1111/j.1749-6632.1998.tb11189.x.

VIP and breast cancer

T W Moody  1 , J Leyton, I Gozes, L Lang, W C Eckelman
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VIP and breast cancer

T W Moody et al. Ann N Y Acad Sci. .

Abstract

VIP1 receptors are present in breast cancer cells. VIP elevates the cAMP and stimulates nuclear oncogene expression in MCF-7 cells. VIPhybrid is a VIP receptor antagonist that inhibits breast cancer proliferation. A VIP analog has been developed for imaging breast tumors. Therefore VIP1 receptors may be utilized for the early detection and treatment of breast cancer.

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