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. 1998 Dec 15;8(24):3475-8.
doi: 10.1016/s0960-894x(98)00628-3.

Anti-HIV coumarins from Calophyllum seed oil

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Anti-HIV coumarins from Calophyllum seed oil

C Spino et al. Bioorg Med Chem Lett. .

Abstract

The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.

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