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. 1978 Jul 18;41(4):323-8.
doi: 10.1007/BF01871996.

Effect of sodium transport inhibition on active phosphate transport by toad bladder

B B Sellers Jr, J A Hall, S A Mendoza

Effect of sodium transport inhibition on active phosphate transport by toad bladder

B B Sellers Jr et al. J Membr Biol. .

Abstract

The relationship between active Na transport (estimated by the short-circuit (SCC)) and active inorganic phosphate (Pi) transport was studied in the toad bladder. When SCC was inhibited by amiloride, ouabain, or removal of K from the serosal bathing solution, active Pi transport was totally inhibited. When Na was replaced isotonically by choline in either the mucosal bathing solution or both the mucosal and serosal bathing solutions, there was no measurable SCC or active Pi transport. These experiments are compatible with the hypothesis that active Pi transport occurs only in the presence of active Na transport.

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