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. 1976 Oct;3(10):2459-70.
doi: 10.1093/nar/3.10.2459.

Models of triple-stranded polynucleotides with optimised stereochemistry

S Arnott, P J Bond, E Selsing, P J Smith
Free PMC article

Models of triple-stranded polynucleotides with optimised stereochemistry

S Arnott et al. Nucleic Acids Res. 1976 Oct.
Free PMC article

Abstract

Detailed models are presented for the triple-stranded polynucleotide helices of poly (U)-poly (A)-poly (U) (two forms), poly (U)-poly d (A) -poly (U), poly d(C)-poly d(I)-poly d(C), poly d(T)-polyd(A)-poly d(T) and poly (I)-poly (A)-poly (I). The models were genrated using a computerized, linked-atom procedure which preserves standard bond lengths, bond anglesand sugar ring conformations, constrains the helices to have the pitches and symmetries observed in X-ray diffraction experiments, and optimises the non-bonded interatomic contacts including hydrogen bonds. The possible biological sigificance of such complexes is discussed.

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References

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