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Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane.
Bymaster FP, Shannon HE, Rasmussen K, Delapp NW, Mitch CH, Ward JS, Calligaro DO, Ludvigsen TS, Sheardown MJ, Olesen PH, Swedberg MD, Sauerberg P, Fink-Jensen A. Bymaster FP, et al. Among authors: ward js. Eur J Pharmacol. 1998 Sep 4;356(2-3):109-19. doi: 10.1016/s0014-2999(98)00487-7. Eur J Pharmacol. 1998. PMID: 9774240
Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity.
Sauerberg P, Jeppesen L, Olesen PH, Rasmussen T, Swedberg MD, Sheardown MJ, Fink-Jensen A, Thomsen C, Thøgersen H, Rimvall K, Ward JS, Calligaro DO, DeLapp NW, Bymaster FP, Shannon HE. Sauerberg P, et al. Among authors: ward js. J Med Chem. 1998 Oct 22;41(22):4378-84. doi: 10.1021/jm981048e. J Med Chem. 1998. PMID: 9784113
234 results