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Overexpression of the Golgi-localized enzyme alpha-mannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway.
Oh-Eda M, Nakagawa H, Akama TO, Lowitz K, Misago M, Moremen KW, Fukuda MN. Oh-Eda M, et al. Among authors: akama to. Eur J Biochem. 2001 Mar;268(5):1280-8. doi: 10.1046/j.1432-1327.2001.01992.x. Eur J Biochem. 2001. PMID: 11231279 Free article.
The role of N-glycans in spermatogenesis.
Fukuda MN, Akama TO. Fukuda MN, et al. Among authors: akama to. Cytogenet Genome Res. 2003;103(3-4):302-6. doi: 10.1159/000076817. Cytogenet Genome Res. 2003. PMID: 15051952 Review.
Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.
Akama TO, Misra AK, Hindsgaul O, Fukuda MN. Akama TO, et al. J Biol Chem. 2002 Nov 8;277(45):42505-13. doi: 10.1074/jbc.M207412200. Epub 2002 Sep 5. J Biol Chem. 2002. PMID: 12218059 Free article.
In the previous study, we found that hCGn6ST and mIGn6ST, but not hIGn6ST, have sulfotransferase activity to produce keratan sulfate (Akama, T. O., Nakayama, J., Nishida, K., Hiraoka, N., Suzuki, M., McAuliffe, J., Hindsgaul, O., Fukuda, M., and Fukuda, M. ...Using …
In the previous study, we found that hCGn6ST and mIGn6ST, but not hIGn6ST, have sulfotransferase activity to produce keratan sulfate …
Unusual N-glycan structures in alpha-mannosidase II/IIx double null embryos identified by a systematic glycomics approach based on two-dimensional LC mapping and matrix-dependent selective fragmentation method in MALDI-TOF/TOF mass spectrometry.
Hato M, Nakagawa H, Kurogochi M, Akama TO, Marth JD, Fukuda MN, Nishimura S. Hato M, et al. Among authors: akama to. Mol Cell Proteomics. 2006 Nov;5(11):2146-57. doi: 10.1074/mcp.M600213-MCP200. Epub 2006 Aug 9. Mol Cell Proteomics. 2006. PMID: 16899540 Free article.
alpha-Mannosidase IIx (MX) is an enzyme closely related to alpha-mannosidase II (MII), a key enzyme in N-glycan biosynthesis that catalyzes the first step in conversion of hybrid- to complex-type N-glycans in Golgi apparatus. Recently we generated MII/MX double knoc …
alpha-Mannosidase IIx (MX) is an enzyme closely related to alpha-mannosidase II (MII), a key enzyme in N-glycan biosynthesis that cat …
71 results