Spring DR - Search Results

1

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Spring DR, Krishnan S, Blackwell HE, Schreiber SL. Spring DR, et al. J Am Chem Soc. 2002 Feb 20;124(7):1354-63. doi: 10.1021/ja017248o. J Am Chem Soc. 2002. PMID: 11841305

2

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: spring dr. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

3

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips.

Huang J, Zhu H, Haggarty SJ, Spring DR, Hwang H, Jin F, Snyder M, Schreiber SL. Huang J, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16594-9. doi: 10.1073/pnas.0407117101. Epub 2004 Nov 11. Proc Natl Acad Sci U S A. 2004. PMID: 15539461 Free PMC article.

4

Aryl-aryl coupling via directed lithiation and oxidation.

Surry DS, Fox DJ, Macdonald SJ, Spring DR. Surry DS, et al. Among authors: spring dr. Chem Commun (Camb). 2005 May 28;(20):2589-90. doi: 10.1039/b501939g. Epub 2005 Apr 12. Chem Commun (Camb). 2005. PMID: 15900336

5

Assessment of structural diversity in combinatorial synthesis.

Fergus S, Bender A, Spring DR. Fergus S, et al. Among authors: spring dr. Curr Opin Chem Biol. 2005 Jun;9(3):304-9. doi: 10.1016/j.cbpa.2005.03.004. Curr Opin Chem Biol. 2005. PMID: 15939333 Review.

6

Diversity-oriented synthesis.

Spandl RJ, Díaz-Gavilán M, O'Connell KM, Thomas GL, Spring DR. Spandl RJ, et al. Among authors: spring dr. Chem Rec. 2008;8(3):129-42. doi: 10.1002/tcr.20144. Chem Rec. 2008. PMID: 18563806

7

Exploiting domino enyne metathesis mechanisms for skeletal diversity generation.

Spandl RJ, Rudyk H, Spring DR. Spandl RJ, et al. Among authors: spring dr. Chem Commun (Camb). 2008 Jul 14;(26):3001-3. doi: 10.1039/b807278g. Epub 2008 Jun 3. Chem Commun (Camb). 2008. PMID: 18688328

8

Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis.

Wyatt EE, Galloway WR, Thomas GL, Welch M, Loiseleur O, Plowright AT, Spring DR. Wyatt EE, et al. Among authors: spring dr. Chem Commun (Camb). 2008 Oct 28;(40):4962-4. doi: 10.1039/b812901k. Epub 2008 Sep 10. Chem Commun (Camb). 2008. PMID: 18931753

9

The discovery of antibacterial agents using diversity-oriented synthesis.

Galloway WR, Bender A, Welch M, Spring DR. Galloway WR, et al. Among authors: spring dr. Chem Commun (Camb). 2009 May 14;(18):2446-62. doi: 10.1039/b816852k. Epub 2009 Apr 1. Chem Commun (Camb). 2009. PMID: 19532856 Review.

10

Diversity-oriented synthesis of bicyclic and tricyclic alkaloids.

Díaz-Gavilán M, Galloway WR, O'Connell KM, Hodkingson JT, Spring DR. Díaz-Gavilán M, et al. Among authors: spring dr. Chem Commun (Camb). 2010 Feb 7;46(5):776-8. doi: 10.1039/b917965h. Epub 2009 Dec 14. Chem Commun (Camb). 2010. PMID: 20087517

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