Clements JM - Search Results

1

Antibacterial activities and characterization of novel inhibitors of LpxC.

Clements JM, Coignard F, Johnson I, Chandler S, Palan S, Waller A, Wijkmans J, Hunter MG. Clements JM, et al. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9. doi: 10.1128/AAC.46.6.1793-1799.2002. Antimicrob Agents Chemother. 2002. PMID: 12019092 Free PMC article.

2

Novel approaches to antimicrobial therapy: peptide deformylase.

Waller AS, Clements JM. Waller AS, et al. Among authors: clements jm. Curr Opin Drug Discov Devel. 2002 Sep;5(5):785-92. Curr Opin Drug Discov Devel. 2002. PMID: 12630299 Review.

3

In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698.

Lofland D, Difuntorum S, Waller A, Clements JM, Weaver MK, Karlowsky JA, Johnson K. Lofland D, et al. Among authors: clements jm. J Antimicrob Chemother. 2004 Apr;53(4):664-8. doi: 10.1093/jac/dkh129. Epub 2004 Feb 18. J Antimicrob Chemother. 2004. PMID: 14973152

4

Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.

Gross M, Clements J, Beckett RP, Thomas W, Taylor S, Lofland D, Ramanathan-Girish S, Garcia M, Difuntorum S, Hoch U, Chen H, Johnson KW. Gross M, et al. J Antimicrob Chemother. 2004 Mar;53(3):487-93. doi: 10.1093/jac/dkh108. Epub 2004 Feb 12. J Antimicrob Chemother. 2004. PMID: 14963065

5

Peptide deformylase inhibitors with activity against respiratory tract pathogens.

East SP, Beckett RP, Brookings DC, Clements JM, Doel S, Keavey K, Pain G, Smith HK, Thomas W, Thompson AJ, Todd RS, Whittaker M. East SP, et al. Among authors: clements jm. Bioorg Med Chem Lett. 2004 Jan 5;14(1):59-62. doi: 10.1016/j.bmcl.2003.10.013. Bioorg Med Chem Lett. 2004. PMID: 14684298

6

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group.

Smith HK, Beckett RP, Clements JM, Doel S, East SP, Launchbury SB, Pratt LM, Spavold ZM, Thomas W, Todd RS, Whittaker M. Smith HK, et al. Among authors: clements jm. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3595-9. doi: 10.1016/s0960-894x(02)00790-4. Bioorg Med Chem Lett. 2002. PMID: 12443784

7

Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains.

Davies SJ, Ayscough AP, Beckett RP, Clements JM, Doel S, Pratt LM, Spavold ZM, Thomas SW, Whittaker M. Davies SJ, et al. Among authors: clements jm. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2715-8. doi: 10.1016/s0960-894x(03)00533-x. Bioorg Med Chem Lett. 2003. PMID: 12873500

8

Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor.

Ramanathan-Girish S, McColm J, Clements JM, Taupin P, Barrowcliffe S, Hevizi J, Safrin S, Moore C, Patou G, Moser H, Gadd A, Hoch U, Jiang V, Lofland D, Johnson KW. Ramanathan-Girish S, et al. Among authors: clements jm. Antimicrob Agents Chemother. 2004 Dec;48(12):4835-42. doi: 10.1128/AAC.48.12.4835-4842.2004. Antimicrob Agents Chemother. 2004. PMID: 15561864 Free PMC article. Clinical Trial.

9

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain.

Davies SJ, Ayscough AP, Beckett RP, Bragg RA, Clements JM, Doel S, Grew C, Launchbury SB, Perkins GM, Pratt LM, Smith HK, Spavold ZM, Thomas SW, Todd RS, Whittaker M. Davies SJ, et al. Among authors: clements jm. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2709-13. doi: 10.1016/s0960-894x(03)00532-8. Bioorg Med Chem Lett. 2003. PMID: 12873499

10

Petersen's Hernia With a Twist.

Clements J, Clements BW, Clements JM. Clements J, et al. Among authors: clements jm. Cureus. 2025 Feb 2;17(2):e78370. doi: 10.7759/cureus.78370. eCollection 2025 Feb. Cureus. 2025. PMID: 40041631 Free PMC article.

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