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Page 1
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.
Zhang YD, Hurson AN, Zhang H, Choudhury PP, Easton DF, Milne RL, Simard J, Hall P, Michailidou K, Dennis J, Schmidt MK, Chang-Claude J, Gharahkhani P, Whiteman D, Campbell PT, Hoffmeister M, Jenkins M, Peters U, Hsu L, Gruber SB, Casey G, Schmit SL, O'Mara TA, Spurdle AB, Thompson DJ, Tomlinson I, De Vivo I, Landi MT, Law MH, Iles MM, Demenais F, Kumar R, MacGregor S, Bishop DT, Ward SV, Bondy ML, Houlston R, Wiencke JK, Melin B, Barnholtz-Sloan J, Kinnersley B, Wrensch MR, Amos CI, Hung RJ, Brennan P, McKay J, Caporaso NE, Berndt SI, Birmann BM, Camp NJ, Kraft P, Rothman N, Slager SL, Berchuck A, Pharoah PDP, Sellers TA, Gayther SA, Pearce CL, Goode EL, Schildkraut JM, Moysich KB, Amundadottir LT, Jacobs EJ, Klein AP, Petersen GM, Risch HA, Stolzenberg-Solomon RZ, Wolpin BM, Li D, Eeles RA, Haiman CA, Kote-Jarai Z, Schumacher FR, Al Olama AA, Purdue MP, Scelo G, Dalgaard MD, Greene MH, Grotmol T, Kanetsky PA, McGlynn KA, Nathanson KL, Turnbull C, Wiklund F; Breast Cancer Association Consortium (BCAC); Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON); Colon Cancer Family Registry (CCFR); Transdisciplinary Studies of Genetic Variation in Colorectal Cancer (CORECT)… See abstract for full author list ➔ Zhang YD, et al. Among authors: gruber sb. Nat Commun. 2020 Jul 3;11(1):3353. doi: 10.1038/s41467-020-16483-3. Nat Commun. 2020. PMID: 32620889 Free PMC article.
Body mass index and molecular subtypes of colorectal cancer.
Murphy N, Newton CC, Song M, Papadimitriou N, Hoffmeister M, Phipps AI, Harrison TA, Newcomb PA, Aglago EK, Berndt SI, Brenner H, Buchanan DD, Cao Y, Chan AT, Chen X, Cheng I, Chang-Claude J, Dimou N, Drew D, Farris AB, French AJ, Gallinger S, Georgeson P, Giannakis M, Giles GG, Gruber SB, Harlid S, Hsu L, Huang WY, Jenkins MA, Laskar RS, Le Marchand L, Limburg P, Lin Y, Mandic M, Nowak JA, Obón-Santacana M, Ogino S, Qu C, Sakoda LC, Schoen RE, Southey MC, Stadler ZK, Steinfelder RS, Sun W, Thibodeau SN, Toland AE, Trinh QM, Tsilidis KK, Ugai T, Van Guelpen B, Wang X, Woods MO, Zaidi SH, Gunter MJ, Peters U, Campbell PT. Murphy N, et al. Among authors: gruber sb. J Natl Cancer Inst. 2023 Feb 8;115(2):165-173. doi: 10.1093/jnci/djac215. J Natl Cancer Inst. 2023. PMID: 36445035 Free PMC article.
Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes.
Harrison TA, Zaidi SH, Yin H, Steinfelder RS, Qu C, Aglago EK, Berndt SI, Boardman LA, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Chanock SJ, Doheny KF, Drew DA, Figueiredo JC, French AJ, Gallinger S, Georgeson P, Giannakis M, Goode EL, Gruber SB, Gsur A, Gunter MJ, Harlid S, Hoffmeister M, Huang WY, Hullar MA, Huyghe JR, Jenkins MA, Lin Y, Moreno V, Murphy N, Newcomb PA, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Shelford T, Song M, Thomas CE, Toland AE, Ugai T, Um CY, Van Guelpen B, Trinh QM, Sun W, Hudson TJ, Hsu L, Peters U, Phipps AI. Harrison TA, et al. Among authors: gruber sb. BMC Cancer. 2025 Dec 18. doi: 10.1186/s12885-025-15440-x. Online ahead of print. BMC Cancer. 2025. PMID: 41413856 Free article.
Variant-Specific Mendelian Risk Prediction Model.
Dias JA, Bae E, Huang T, Chen J, Gruber SB, Idos G, Parmigiani G, Rebbeck TR, Braun D. Dias JA, et al. Among authors: gruber sb. Stat Med. 2025 Dec;44(28-30):e70342. doi: 10.1002/sim.70342. Stat Med. 2025. PMID: 41365806
Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention.
Li Q, Song Q, Chen Z, Choi J, Moreno V, Ping J, Wen W, Li C, Shu X, Yan J, Shu XO, Cai Q, Long J, Huyghe JR, Pai R, Gruber SB, Yang Y, Casey G, Wang X, Toriola AT, Li L, Singh B, Lau KS, Zhou L, Zhang Z, Wu C, Peters U, Zheng W, Long Q, Yin Z, Guo X. Li Q, et al. Among authors: gruber sb. Am J Hum Genet. 2025 Dec 2:S0002-9297(25)00433-1. doi: 10.1016/j.ajhg.2025.11.008. Online ahead of print. Am J Hum Genet. 2025. PMID: 41338217
Using gene-environment interactions to explore pathways for colorectal cancer risk.
Bouras E, Yu R, Kim AE, Markozannes G, Murphy N, Albanes D, Anderson LN, Barry EL, Berndt SI, Bishop DT, Brenner H, Burnett-Hartman A, Campbell PT, Carreras-Torres R, Chan AT, Cheng I, Devall MA, Diez-Obrero V, Dimou N, Drew DA, Gruber SB, Gsur A, Hoffmeister M, Hsu L, Huyghe JR, Kawaguchi E, Keku TO, Kundaje A, Küry S, Le Marchand L, Lewinger JP, Li L, Lynch BM, Moreno V, Morrison JL, Newton CC, Obón-Santacana M, Palmer JR, Papadimitriou N, Pellatt AJ, Peoples AR, Pharoah PDP, Platz EA, Qu C, Ruiz-Narvaez E, Mendez JS, Schoen RE, Stern MC, Thomas CE, Tian Y, Um CY, Visvanathan K, Vodicka P, Vymetalkova V, White E, Wolk A, Woods MO, Wu AH, Gunter MJ, Gauderman WJ, Peters U, Evangelou M, Tsilidis KK. Bouras E, et al. Among authors: gruber sb. EBioMedicine. 2025 Nov;121:105964. doi: 10.1016/j.ebiom.2025.105964. Epub 2025 Oct 11. EBioMedicine. 2025. PMID: 41076992 Free PMC article.
Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study.
Chalitsios CV, Markozannes G, Aglago EK, Berndt SI, Buchanan DD, Campbell PT, Cao Y, Chan AT, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Gruber SB, Gunter MJ, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Hullar MAJ, Huyghe JR, Lynch BM, Moreno V, Murphy N, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Qu C, Schmit SL, Steinfelder RS, Sun W, Thomas CE, Toland AE, Trinh QM, Ugai T, Um CY, Guelpen BV, Zaidi SH, Schoen RE, Woods MO, Brenner H, Andreson L, Pellatt AJ, Peters U, Phipps AI, Tsilidis KK. Chalitsios CV, et al. Among authors: gruber sb. JNCI Cancer Spectr. 2025 Nov 3;9(6):pkaf095. doi: 10.1093/jncics/pkaf095. JNCI Cancer Spectr. 2025. PMID: 41031512 Free PMC article.
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.
Hazelwood E, Goudswaard LJ, Lee MA, Vabistsevits M, Pournaras DJ, Brenner H, Buchanan DD, Gruber SB, Gsur A, Li L, Vodickova L, Grant RC, Samadder NJ, Timpson NJ, Gunter MJ, Schuster-Böckler B, Yarmolinsky J, Richardson TG, Freisling H, Murphy N, Vincent EE. Hazelwood E, et al. Among authors: gruber sb. J Natl Cancer Inst. 2025 Dec 1;117(12):2621-2642. doi: 10.1093/jnci/djaf201. J Natl Cancer Inst. 2025. PMID: 40987470 Free PMC article.
365 results