Stepkowski SM - Search Results

1

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

Nagy ZS, Wang Y, Erwin-Cohen RA, Aradi J, Monia B, Wang LH, Stepkowski SM, Rui H, Kirken RA. Nagy ZS, et al. Among authors: stepkowski sm. J Leukoc Biol. 2002 Oct;72(4):819-28. J Leukoc Biol. 2002. PMID: 12377952

2

Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.

Stepkowski SM, Erwin-Cohen RA, Behbod F, Wang ME, Qu X, Tejpal N, Nagy ZS, Kahan BD, Kirken RA. Stepkowski SM, et al. Blood. 2002 Jan 15;99(2):680-9. doi: 10.1182/blood.v99.2.680. Blood. 2002. PMID: 11781254 Free article.

3

Specific inhibition of Stat5a/b promotes apoptosis of IL-2-responsive primary and tumor-derived lymphoid cells.

Behbod F, Nagy ZS, Stepkowski SM, Karras J, Johnson CR, Jarvis WD, Kirken RA. Behbod F, et al. Among authors: stepkowski sm. J Immunol. 2003 Oct 15;171(8):3919-27. doi: 10.4049/jimmunol.171.8.3919. J Immunol. 2003. PMID: 14530308

4

Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.

Behbod F, Erwin-Cohen RA, Wang ME, Trawick BW, Qu X, Verani R, Kahan BD, Stepkowski SM, Kirken RA. Behbod F, et al. Among authors: stepkowski sm. J Immunol. 2001 Mar 15;166(6):3724-32. doi: 10.4049/jimmunol.166.6.3724. J Immunol. 2001. PMID: 11238613

5

Regulation of lymphoid cell apoptosis by Jaks and Stats.

Nagy ZS, Ross J, Cheng H, Stepkowski SM, Kirken RA. Nagy ZS, et al. Among authors: stepkowski sm. Crit Rev Immunol. 2004;24(2):87-110. doi: 10.1615/critrevimmunol.v24.i2.10. Crit Rev Immunol. 2004. PMID: 15581392 Review.

6

Janus tyrosine kinases and signal transducers and activators of transcription regulate critical functions of T cells in allograft rejection and transplantation tolerance.

Stepkowski SM, Kirken RA. Stepkowski SM, et al. Transplantation. 2006 Aug 15;82(3):295-303. doi: 10.1097/01.tp.0000228903.03118.be. Transplantation. 2006. PMID: 16906023 Review.

7

A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor.

Nagy ZS, Rui H, Stepkowski SM, Karras J, Kirken RA. Nagy ZS, et al. Among authors: stepkowski sm. J Immunol. 2006 Oct 15;177(8):5032-40. doi: 10.4049/jimmunol.177.8.5032. J Immunol. 2006. PMID: 17015686

8

Regulation of T cell homeostasis by JAKs and STATs.

Ross JA, Nagy ZS, Cheng H, Stepkowski SM, Kirken RA. Ross JA, et al. Among authors: stepkowski sm. Arch Immunol Ther Exp (Warsz). 2007 Jul-Aug;55(4):231-45. doi: 10.1007/s00005-007-0030-x. Epub 2007 Jul 23. Arch Immunol Ther Exp (Warsz). 2007. PMID: 17659375 Review.

9

The role of IL-2 in allograft rejection--a lesson learned from experimental work.

Stepkowski SM, Kirken RA. Stepkowski SM, et al. Transplantation. 2000 Jun 27;69(12):2480-2. doi: 10.1097/00007890-200006270-00003. Transplantation. 2000. PMID: 10910265 No abstract available.

10

Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts.

Kirken RA, Erwin-Cohen R, Behbod F, Wang M, Stepkowski SM, Kahan BD. Kirken RA, et al. Among authors: stepkowski sm. Transplant Proc. 2001 Feb-Mar;33(1-2):95. doi: 10.1016/s0041-1345(00)02791-3. Transplant Proc. 2001. PMID: 11266723 No abstract available.

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