Mathew JS - Search Results

1

l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.

Chong Y, Gumina G, Mathew JS, Schinazi RF, Chu CK. Chong Y, et al. Among authors: mathew js. J Med Chem. 2003 Jul 17;46(15):3245-56. doi: 10.1021/jm0300274. J Med Chem. 2003. PMID: 12852755

2

2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.

Shi J, Ray AS, Mathew JS, Anderson KS, Chu CK, Schinazi RF. Shi J, et al. Among authors: mathew js. Bioorg Med Chem Lett. 2004 May 3;14(9):2159-62. doi: 10.1016/j.bmcl.2004.02.031. Bioorg Med Chem Lett. 2004. PMID: 15081000

3

Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.

Chong Y, Choo H, Choi Y, Mathew J, Schinazi RF, Chu CK. Chong Y, et al. J Med Chem. 2002 Oct 24;45(22):4888-98. doi: 10.1021/jm020246+. J Med Chem. 2002. PMID: 12383014

4

Synthesis, anti-HIV activity, and molecular mechanism of drug resistance of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.

Choo H, Chong Y, Choi Y, Mathew J, Schinazi RF, Chu CK. Choo H, et al. J Med Chem. 2003 Jan 30;46(3):389-98. doi: 10.1021/jm020376i. J Med Chem. 2003. PMID: 12540238

5

Antiviral activities and cellular toxicities of modified 2',3'-dideoxy-2',3'-didehydrocytidine analogues.

Stuyver LJ, Lostia S, Adams M, Mathew JS, Pai BS, Grier J, Tharnish PM, Choi Y, Chong Y, Choo H, Chu CK, Otto MJ, Schinazi RF. Stuyver LJ, et al. Among authors: mathew js. Antimicrob Agents Chemother. 2002 Dec;46(12):3854-60. doi: 10.1128/AAC.46.12.3854-3860.2002. Antimicrob Agents Chemother. 2002. PMID: 12435688 Free PMC article.

6

Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.

Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: mathew js. Antimicrob Agents Chemother. 2005 May;49(5):1994-2001. doi: 10.1128/AAC.49.5.1994-2001.2005. Antimicrob Agents Chemother. 2005. PMID: 15855524 Free PMC article.

7

N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.

Shi J, Mathew JS, Tharnish PM, Rachakonda S, Pai SB, Adams M, Grier JP, Gallagher K, Zhang H, Wu JT, Shi G, Geleziunas R, Erickson-Viitanen S, Stuyver L, Otto MJ, Watanabe KA, Schinazi RF. Shi J, et al. Among authors: mathew js. Antivir Chem Chemother. 2003 Mar;14(2):81-90. doi: 10.1177/095632020301400203. Antivir Chem Chemother. 2003. PMID: 12856919 Free article.

8

Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine.

Hernandez-Santiago BI, Mathew JS, Rapp KL, Grier JP, Schinazi RF. Hernandez-Santiago BI, et al. Among authors: mathew js. Antimicrob Agents Chemother. 2007 Jun;51(6):2130-5. doi: 10.1128/AAC.01543-06. Epub 2007 Apr 2. Antimicrob Agents Chemother. 2007. PMID: 17403996 Free PMC article.

9

Phenolics with antiviral activity from Millettia erythrocalyx and Artocarpus lakoocha.

Likhitwitayawuid K, Sritularak B, Benchanak K, Lipipun V, Mathew J, Schinazi RF. Likhitwitayawuid K, et al. Nat Prod Res. 2005 Feb;19(2):177-82. doi: 10.1080/14786410410001704813. Nat Prod Res. 2005. PMID: 15715263

10

Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals.

Murphy RL, Kivel NM, Zala C, Ochoa C, Tharnish P, Mathew J, Pascual ML, Schinazi RF. Murphy RL, et al. Antivir Ther. 2010;15(2):185-92. doi: 10.3851/IMP1514. Antivir Ther. 2010. PMID: 20386073 Free PMC article. Clinical Trial.

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