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Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors.
Salami A, Adiele U, Coate G, Diolaiti M, Chen H, Lu J, Ashworth A, Patil M, Fleishman JS, Ramaraju A, Patel A, Patel H, Patel K, Murakami M, Ambudkar SV, Talele TT. Salami A, et al. Among authors: ashworth a. Bioorg Chem. 2025 Oct;165:108941. doi: 10.1016/j.bioorg.2025.108941. Epub 2025 Sep 5. Bioorg Chem. 2025. PMID: 40945025
Confirmation of BIK and SAMHD1 as Prostate Cancer Susceptibility Genes.
Pavlovich CP, Wei J, Gielzak M, Shi Z, Tran H, Ashworth A, Lilly Zheng S, Walsh PC, Luo J, Helfand BT, Isaacs WB, Xu J. Pavlovich CP, et al. Among authors: ashworth a. Prostate. 2025 Aug 18. doi: 10.1002/pros.70037. Online ahead of print. Prostate. 2025. PMID: 40825105
AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid.
Chen DF, Roe LT, Yuping L, Borges AL, Zhang JY, Babbar P, Maji S, Stevens MGV, Correy GJ, Diolaiti ME, Smith DH, Ashworth A, Stroud RM, Kelly MJS, Bondy-Denomy J, Fraser JS. Chen DF, et al. Among authors: ashworth a. mBio. 2025 Sep 10;16(9):e0169825. doi: 10.1128/mbio.01698-25. Epub 2025 Aug 14. mBio. 2025. PMID: 40810510 Free PMC article.
Superior performance of two combined polygenic scores for predicting skin cancer risk and differentiating risk of melanoma from keratinocyte carcinomas in two cohorts.
Liu L, Tran H, Mulford AJ, Shi Z, Wei J, Ashworth A, Zheng SL, Waldinger JB, Levy RM, Sanders AR, Xu J. Liu L, et al. Among authors: ashworth a. JAAD Int. 2025 Jun 6;21:70-72. doi: 10.1016/j.jdin.2025.03.004. eCollection 2025 Aug. JAAD Int. 2025. PMID: 40689051 Free PMC article. No abstract available.
872 results