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Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.
Okunade GW, Miller ML, Pyne GJ, Sutliff RL, O'Connor KT, Neumann JC, Andringa A, Miller DA, Prasad V, Doetschman T, Paul RJ, Shull GE. Okunade GW, et al. Among authors: miller ml, miller da. J Biol Chem. 2004 Aug 6;279(32):33742-50. doi: 10.1074/jbc.M404628200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178683 Free article.
Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric.
Gawenis LR, Ledoussal C, Judd LM, Prasad V, Alper SL, Stuart-Tilley A, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Gawenis LR, et al. Among authors: miller ml. J Biol Chem. 2004 Jul 16;279(29):30531-9. doi: 10.1074/jbc.M403779200. Epub 2004 Apr 30. J Biol Chem. 2004. PMID: 15123620 Free article.
Phenotypes of SERCA and PMCA knockout mice.
Prasad V, Okunade GW, Miller ML, Shull GE. Prasad V, et al. Among authors: miller ml. Biochem Biophys Res Commun. 2004 Oct 1;322(4):1192-203. doi: 10.1016/j.bbrc.2004.07.156. Biochem Biophys Res Commun. 2004. PMID: 15336967 Review.
Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.
Prasad V, Bodi I, Meyer JW, Wang Y, Ashraf M, Engle SJ, Doetschman T, Sisco K, Nieman ML, Miller ML, Lorenz JN, Shull GE. Prasad V, et al. Among authors: miller ml. J Biol Chem. 2008 Nov 14;283(46):31303-14. doi: 10.1074/jbc.M803706200. Epub 2008 Sep 8. J Biol Chem. 2008. PMID: 18779325 Free PMC article.
742 results