Spring DR - Search Results

1

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips.

Huang J, Zhu H, Haggarty SJ, Spring DR, Hwang H, Jin F, Snyder M, Schreiber SL. Huang J, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16594-9. doi: 10.1073/pnas.0407117101. Epub 2004 Nov 11. Proc Natl Acad Sci U S A. 2004. PMID: 15539461 Free PMC article.

2

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: spring dr. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

3

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Spring DR, Krishnan S, Blackwell HE, Schreiber SL. Spring DR, et al. J Am Chem Soc. 2002 Feb 20;124(7):1354-63. doi: 10.1021/ja017248o. J Am Chem Soc. 2002. PMID: 11841305

4

Chemical genetics to chemical genomics: small molecules offer big insights.

Spring DR. Spring DR. Chem Soc Rev. 2005 Jun;34(6):472-82. doi: 10.1039/b312875j. Chem Soc Rev. 2005. PMID: 16137160 Review.

5

Diversity-oriented synthesis of macrocyclic peptidomimetics.

Isidro-Llobet A, Murillo T, Bello P, Cilibrizzi A, Hodgkinson JT, Galloway WR, Bender A, Welch M, Spring DR. Isidro-Llobet A, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6793-8. doi: 10.1073/pnas.1015267108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383137 Free PMC article.

6

Chemical genetics.

O'Connor CJ, Laraia L, Spring DR. O'Connor CJ, et al. Among authors: spring dr. Chem Soc Rev. 2011 Aug;40(8):4332-45. doi: 10.1039/c1cs15053g. Epub 2011 May 12. Chem Soc Rev. 2011. PMID: 21562678 Review.

7

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium.

Ramsay JP, Williamson NR, Spring DR, Salmond GP. Ramsay JP, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14932-7. doi: 10.1073/pnas.1109169108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873216 Free PMC article.

8

Small-molecule screening: advances in microarraying and cell-imaging technologies.

Nicholson RL, Welch M, Ladlow M, Spring DR. Nicholson RL, et al. Among authors: spring dr. ACS Chem Biol. 2007 Jan 23;2(1):24-30. doi: 10.1021/cb600321j. ACS Chem Biol. 2007. PMID: 17243780 Review.

9

The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance.

Lake MA, Adams KN, Nie F, Fowler E, Verma AK, Dei S, Teodori E, Sherman DR, Edelstein PH, Spring DR, Troll M, Ramakrishnan L. Lake MA, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215512120. doi: 10.1073/pnas.2215512120. Epub 2023 Feb 10. Proc Natl Acad Sci U S A. 2023. PMID: 36763530 Free PMC article.

10

The discovery of antibacterial agents using diversity-oriented synthesis.

Galloway WR, Bender A, Welch M, Spring DR. Galloway WR, et al. Among authors: spring dr. Chem Commun (Camb). 2009 May 14;(18):2446-62. doi: 10.1039/b816852k. Epub 2009 Apr 1. Chem Commun (Camb). 2009. PMID: 19532856 Review.

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