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A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development.
Robinson S, Delongeas JL, Donald E, Dreher D, Festag M, Kervyn S, Lampo A, Nahas K, Nogues V, Ockert D, Quinn K, Old S, Pickersgill N, Somers K, Stark C, Stei P, Waterson L, Chapman K. Robinson S, et al. Among authors: stark c. Regul Toxicol Pharmacol. 2008 Apr;50(3):345-52. doi: 10.1016/j.yrtph.2007.11.009. Epub 2007 Dec 5. Regul Toxicol Pharmacol. 2008. PMID: 18295384
A global pharmaceutical company initiative: an evidence-based approach to define the upper limit of body weight loss in short term toxicity studies.
Chapman K, Sewell F, Allais L, Delongeas JL, Donald E, Festag M, Kervyn S, Ockert D, Nogues V, Palmer H, Popovic M, Roosen W, Schoenmakers A, Somers K, Stark C, Stei P, Robinson S. Chapman K, et al. Among authors: stark c. Regul Toxicol Pharmacol. 2013 Oct;67(1):27-38. doi: 10.1016/j.yrtph.2013.04.003. Epub 2013 Apr 19. Regul Toxicol Pharmacol. 2013. PMID: 23602904 Free article.
Science-Based Approach to Harmonize Contraception Recommendations in Clinical Trials and Pharmaceutical Labels.
Bowman CJ, Becourt-Lhote N, Boulifard V, Cordts R, Corriol-Rohou S, Enright B, Erkman L, Harris J, Hartmann A, Hilpert J, Kervyn S, Mattson B, Morford L, Muller M, Powell M, Sobol Z, Srinivasan R, Stark C, Thompson KE, Turner KJ, Barrow P. Bowman CJ, et al. Among authors: stark c. Clin Pharmacol Ther. 2023 Feb;113(2):226-245. doi: 10.1002/cpt.2602. Epub 2022 May 5. Clin Pharmacol Ther. 2023. PMID: 35388453 Free PMC article. Review.
Vehicle Systems and Excipients Used in Minipig Drug Development Studies.
Weaver ML, Grossi AB, Schützsack J, Parish J, Løgsted J, Bøgh IB, Cameron D, Harvey W, Festag M, Downes N, Venturella S, Schlichtiger J, Mhedhbi S, Ross V, Kissner T, Stark C, Milano S, Heining P, Sanchez-Felix M. Weaver ML, et al. Among authors: stark c. Toxicol Pathol. 2016 Apr;44(3):367-72. doi: 10.1177/0192623315613088. Epub 2015 Dec 16. Toxicol Pathol. 2016. PMID: 26674803 Review.
Nonclinical Safety and Toxicology.
Stark C, Steger-Hartmann T. Stark C, et al. Handb Exp Pharmacol. 2016;232:261-83. doi: 10.1007/164_2015_16. Handb Exp Pharmacol. 2016. PMID: 26489827 Review.
GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.
Abac AG, Abouelfettouh I, Acernese F, Ackley K, Adamcewicz C, Adhicary S, Adhikari D, Adhikari N, Adhikari RX, Adkins VK, Afroz S, Agapito A, Agarwal D, Agathos M, Aggarwal N, Aggarwal S, Aguiar OD, Ahrend IL, Aiello L, Ain A, Ajith P, Akutsu T, Al-Kershi S, Al-Shammari S, Albanesi S, Ali W, Alléné C, Allocca A, Altin PA, Alvarez-Lopez S, Amar W, Amarasinghe O, Amato A, Amicucci F, Amra C, Ananyeva A, Anderson SB, Anderson WG, Andia M, Ando M, Andrés-Carcasona M, Andrić T, Anglin J, Ansoldi S, Antelis JM, Antier S, Aoumi M, Appavuravther EZ, Appert S, Apple SK, Arai K, Araya A, Araya MC, Arca Sedda M, Areeda JS, Aritomi N, Armato F, Armstrong S, Arnaud N, Arogeti M, Aronson SM, Ashton G, Aso Y, Asprea L, Assiduo M, Assis de Souza Melo S, Aston SM, Astone P, Attadio F, Aubin F, AultONeal K, Avallone G, Avila EA, Babak S, Badger C, Bae S, Bagnasco S, Baiotti L, Bajpai R, Baka T, Baker AM, Baker KA, Baker T, Baldi G, Baldicchi N, Ball M, Ballardin G, Ballmer SW, Banagiri S, Banerjee B, Bankar D, Baptiste TM, Baral P, Baratti M, Barayoga JC, Barish BC, Barker D, Barman N, Barneo P, Barone F, Barr B, Barsotti L, Barsuglia M, Barta D, Bartoletti AM, Barton MA, Bartos I, Basalaev A, Bass… See abstract for full author list ➔ Abac AG, et al. Among authors: stark cj. Phys Rev Lett. 2025 Sep 12;135(11):111403. doi: 10.1103/kw5g-d732. Phys Rev Lett. 2025. PMID: 41004747
667 results