Issinger OG - Search Results

1

The 'regulatory' beta-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation.

Bjørling-Poulsen M, Siehler S, Wiesmüller L, Meek D, Niefind K, Issinger OG. Bjørling-Poulsen M, et al. Among authors: issinger og. Oncogene. 2005 Sep 8;24(40):6194-200. doi: 10.1038/sj.onc.1208762. Oncogene. 2005. PMID: 15940255

2

HDM2 negatively affects the Chk2-mediated phosphorylation of p53.

Bjørling-Poulsen M, Meek D, Issinger OG. Bjørling-Poulsen M, et al. Among authors: issinger og. FEBS Lett. 2005 May 9;579(12):2604-8. doi: 10.1016/j.febslet.2005.03.081. Epub 2005 Apr 9. FEBS Lett. 2005. PMID: 15862297 Free article.

3

Structural basis of the constitutive activity of protein kinase CK2.

Olsen BB, Guerra B, Niefind K, Issinger OG. Olsen BB, et al. Among authors: issinger og. Methods Enzymol. 2010;484:515-29. doi: 10.1016/B978-0-12-381298-8.00025-3. Methods Enzymol. 2010. PMID: 21036248

4

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

Ermakova I, Boldyreff B, Issinger OG, Niefind K. Ermakova I, et al. Among authors: issinger og. J Mol Biol. 2003 Jul 25;330(5):925-34. doi: 10.1016/s0022-2836(03)00638-7. J Mol Biol. 2003. PMID: 12860116

5

Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.

Yde CW, Ermakova I, Issinger OG, Niefind K. Yde CW, et al. Among authors: issinger og. J Mol Biol. 2005 Mar 25;347(2):399-414. doi: 10.1016/j.jmb.2005.01.003. Epub 2005 Jan 18. J Mol Biol. 2005. PMID: 15740749

6

Primary and secondary interactions between CK2alpha and CK2beta lead to ring-like structures in the crystals of the CK2 holoenzyme.

Niefind K, Issinger OG. Niefind K, et al. Among authors: issinger og. Mol Cell Biochem. 2005 Jun;274(1-2):3-14. doi: 10.1007/s11010-005-3114-0. Mol Cell Biochem. 2005. PMID: 16335523

7

Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator.

Rasmussen T, Skjøth IH, Jensen HH, Niefind K, Boldyreff B, Issinger OG. Rasmussen T, et al. Among authors: issinger og. Mol Cell Biochem. 2005 Jun;274(1-2):151-61. doi: 10.1007/s11010-005-2944-0. Mol Cell Biochem. 2005. PMID: 16335535

8

Purification and characterization of the CK2alpha'-based holoenzyme, an isozyme of CK2alpha: a comparative analysis.

Olsen BB, Boldyreff B, Niefind K, Issinger OG. Olsen BB, et al. Among authors: issinger og. Protein Expr Purif. 2006 Jun;47(2):651-61. doi: 10.1016/j.pep.2005.12.001. Epub 2005 Dec 27. Protein Expr Purif. 2006. PMID: 16442308

9

The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules.

Raaf J, Brunstein E, Issinger OG, Niefind K. Raaf J, et al. Among authors: issinger og. Chem Biol. 2008 Feb;15(2):111-7. doi: 10.1016/j.chembiol.2007.12.012. Chem Biol. 2008. PMID: 18291315

10

Biochemical characterization of CK2alpha and alpha' paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2alpha'-holoenzyme forming trimeric complexes.

Olsen BB, Rasmussen T, Niefind K, Issinger OG. Olsen BB, et al. Among authors: issinger og. Mol Cell Biochem. 2008 Sep;316(1-2):37-47. doi: 10.1007/s11010-008-9824-3. Epub 2008 Jun 24. Mol Cell Biochem. 2008. PMID: 18574672

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