Riley AM - Search Results

1

Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects.

Maffucci T, Piccolo E, Cumashi A, Iezzi M, Riley AM, Saiardi A, Godage HY, Rossi C, Broggini M, Iacobelli S, Potter BV, Innocenti P, Falasca M. Maffucci T, et al. Among authors: riley am. Cancer Res. 2005 Sep 15;65(18):8339-49. doi: 10.1158/0008-5472.CAN-05-0121. Cancer Res. 2005. PMID: 16166311

2

Unambiguous total synthesis of the enantiomers of myo-inositol 1,3,4-trisphosphate: 1L-myo-inositol 1,3,4-trisphosphate mobilizes intracellular Ca2+ in Limulus photoreceptors.

Riley AM, Payne R, Potter BV. Riley AM, et al. J Med Chem. 1994 Nov 11;37(23):3918-27. doi: 10.1021/jm00049a011. J Med Chem. 1994. PMID: 7966153

3

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates.

Surdo PL, Bottomley MJ, Arcaro A, Siegal G, Panayotou G, Sankar A, Gaffney PR, Riley AM, Potter BV, Waterfield MD, Driscoll PC. Surdo PL, et al. Among authors: riley am. J Biol Chem. 1999 May 28;274(22):15678-85. doi: 10.1074/jbc.274.22.15678. J Biol Chem. 1999. PMID: 10336465 Free article.

4

C-glycoside based mimics of D-myo-inositol 1,4,5-trisphosphate.

Rosenberg HJ, Riley AM, Correa V, Taylor CW, Potter BV. Rosenberg HJ, et al. Among authors: riley am. Carbohydr Res. 2000 Oct 20;329(1):7-16. doi: 10.1016/s0008-6215(00)00175-0. Carbohydr Res. 2000. PMID: 11086681

5

InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase.

Hermosura MC, Takeuchi H, Fleig A, Riley AM, Potter BV, Hirata M, Penner R. Hermosura MC, et al. Among authors: riley am. Nature. 2000 Dec 7;408(6813):735-40. doi: 10.1038/35047115. Nature. 2000. PMID: 11130077

6

Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor.

Nerou EP, Riley AM, Potter BV, Taylor CW. Nerou EP, et al. Among authors: riley am. Biochem J. 2001 Apr 1;355(Pt 1):59-69. doi: 10.1042/0264-6021:3550059. Biochem J. 2001. PMID: 11256949 Free PMC article.

7

Structural determinants of adenophostin A activity at inositol trisphosphate receptors.

Correa V, Riley AM, Shuto S, Horne G, Nerou EP, Marwood RD, Potter BV, Taylor CW. Correa V, et al. Among authors: riley am. Mol Pharmacol. 2001 May;59(5):1206-15. doi: 10.1124/mol.59.5.1206. Mol Pharmacol. 2001. PMID: 11306705

8

Synthesis and biological activity of D- and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of Ins(3,4,5,6)P4 1-kinase/Ins(1,3,4)P3 5/6-kinase.

Liu C, Riley AM, Yang X, Shears SB, Potter BV. Liu C, et al. Among authors: riley am. J Med Chem. 2001 Aug 30;44(18):2984-9. doi: 10.1021/jm000553k. J Med Chem. 2001. PMID: 11520207

9

Chiral Cyclopentane-Based Mimics of D-myo-Inositol 1,4,5-Trisphosphate from D-Glucose.

Jenkins DJ, Riley AM, Potter BV. Jenkins DJ, et al. Among authors: riley am. J Org Chem. 1996 Nov 1;61(22):7719-26. doi: 10.1021/jo961158y. J Org Chem. 1996. PMID: 11667726

10

Adenophostin A and ribophostin, but not inositol 1,4,5-trisphosphate or manno-adenophostin, activate the Ca2+ release-activated Ca2+ current, I(CRAC), in weak intracellular Ca2+ buffer.

Parekh AB, Riley AM, Potter BV. Parekh AB, et al. Among authors: riley am. Biochem J. 2002 Jan 1;361(Pt 1):133-41. doi: 10.1042/0264-6021:3610133. Biochem J. 2002. PMID: 11742538 Free PMC article.

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