Modrich PL - Search Results

1

DNA mismatch repair: functions and mechanisms.

Iyer RR, Pluciennik A, Burdett V, Modrich PL. Iyer RR, et al. Among authors: modrich pl. Chem Rev. 2006 Feb;106(2):302-23. doi: 10.1021/cr0404794. Chem Rev. 2006. PMID: 16464007 Review. No abstract available.

2

Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair.

Pluciennik A, Modrich P. Pluciennik A, et al. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12709-13. doi: 10.1073/pnas.0705129104. Epub 2007 Jul 9. Proc Natl Acad Sci U S A. 2007. PMID: 17620611 Free PMC article.

3

The MutSalpha-proliferating cell nuclear antigen interaction in human DNA mismatch repair.

Iyer RR, Pohlhaus TJ, Chen S, Hura GL, Dzantiev L, Beese LS, Modrich P. Iyer RR, et al. J Biol Chem. 2008 May 9;283(19):13310-9. doi: 10.1074/jbc.M800606200. Epub 2008 Mar 7. J Biol Chem. 2008. PMID: 18326858 Free PMC article.

4

Involvement of the beta clamp in methyl-directed mismatch repair in vitro.

Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Pluciennik A, et al. J Biol Chem. 2009 Nov 20;284(47):32782-91. doi: 10.1074/jbc.M109.054528. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783657 Free PMC article.

5

PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair.

Pluciennik A, Dzantiev L, Iyer RR, Constantin N, Kadyrov FA, Modrich P. Pluciennik A, et al. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16066-71. doi: 10.1073/pnas.1010662107. Epub 2010 Aug 16. Proc Natl Acad Sci U S A. 2010. PMID: 20713735 Free PMC article.

6

Hydrolytic function of Exo1 in mammalian mismatch repair.

Shao H, Baitinger C, Soderblom EJ, Burdett V, Modrich P. Shao H, et al. Nucleic Acids Res. 2014 Jun;42(11):7104-12. doi: 10.1093/nar/gku420. Epub 2014 May 14. Nucleic Acids Res. 2014. PMID: 24829455 Free PMC article.

7

Structure of the human MutSalpha DNA lesion recognition complex.

Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS. Warren JJ, et al. Among authors: modrich pl. Mol Cell. 2007 May 25;26(4):579-92. doi: 10.1016/j.molcel.2007.04.018. Mol Cell. 2007. PMID: 17531815 Free article.

8

Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ.

Tseng Q, Orans J, Hast MA, Iyer RR, Changela A, Modrich PL, Beese LS. Tseng Q, et al. Among authors: modrich pl. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):947-52. doi: 10.1107/S1744309111019300. Epub 2011 Jul 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21821902 Free PMC article.

9

Hydrolytically deficient MutS E694A is defective in the MutL-dependent activation of MutH and in the mismatch-dependent assembly of the MutS.MutL.heteroduplex complex.

Baitinger C, Burdett V, Modrich P. Baitinger C, et al. J Biol Chem. 2003 Dec 5;278(49):49505-11. doi: 10.1074/jbc.M308738200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506224 Free article.

10

A defined human system that supports bidirectional mismatch-provoked excision.

Dzantiev L, Constantin N, Genschel J, Iyer RR, Burgers PM, Modrich P. Dzantiev L, et al. Mol Cell. 2004 Jul 2;15(1):31-41. doi: 10.1016/j.molcel.2004.06.016. Mol Cell. 2004. PMID: 15225546 Free article.

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