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Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore.
Kehlenbeck S, Betz U, Birkmann A, Fast B, Göller AH, Henninger K, Lowinger T, Marrero D, Paessens A, Paulsen D, Pevzner V, Schohe-Loop R, Tsujishita H, Welker R, Kreuter J, Rübsamen-Waigmann H, Dittmer F. Kehlenbeck S, et al. Among authors: schohe loop r. J Virol. 2006 Jul;80(14):6883-94. doi: 10.1128/JVI.00306-06. J Virol. 2006. PMID: 16809294 Free PMC article.