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321 results

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Page 1
Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum.
Webster R, Oyong DA, Llewellyn S, Abd-Rahman AN, Potter AJ, Mukhiya R, Sahai N, Leelasena I, Ujvary E, Mathison S, Andrew DW, Bukali L, de Labastida Rivera F, Engel J, Soon MSF, Frame T, Hamelink J, Nalubega M, Dooley NL, Loughland JR, Nguyen T, Rosenberg-Hasson Y, Maysel-Auslender S, Sigal N, Foygel K, Gower J, Peters J, Woo R, Amante F, Wells TNC, Chalon S, Moehrle JJ, McCarthy JS, Birrell GW, Edstein MD, Leipold M, Obermoser G, Maecker H, Engwerda CR, Barber BE, Boyle MJ. Webster R, et al. Among authors: mccarthy js. Sci Transl Med. 2025 Nov 26;17(826):eaea2531. doi: 10.1126/scitranslmed.aea2531. Epub 2025 Nov 26. Sci Transl Med. 2025. PMID: 41296825 Clinical Trial.
Tfh2 and a subset of Tfh1 cells associate with antibody-mediated immunity to malaria.
Soon MS, Oyong DA, Dooley NL, Mukhiya R, Pava Z, Andrew D, Loughland JR, McCarthy JS, Chan JA, Beeson JG, Engwerda C, Haque A, Boyle MJ. Soon MS, et al. Among authors: mccarthy js. JCI Insight. 2025 Oct 21:e196828. doi: 10.1172/jci.insight.196828. Online ahead of print. JCI Insight. 2025. PMID: 41118256 Free article.
Selecting candidate Neisseria gonorrhoeae strains for oropharyngeal gonorrhoea human challenge: a genomics-based analysis of clinical isolates.
Williams E, Low SJ, Pollock GL, Taouk ML, Prestedge J, Howden BP, Chow EPF, Fairley CK, Seib KL, McCarthy JS, Pasricha S, Williamson DA. Williams E, et al. Among authors: mccarthy js. Lancet Microbe. 2025 Sep;6(9):101105. doi: 10.1016/j.lanmic.2025.101105. Epub 2025 Jul 10. Lancet Microbe. 2025. PMID: 40652955 Free article.
Population pharmacokinetics of penicillin G: insights into increased clearance at low concentrations to guide development of improved long-acting formulations for syphilis and prevention of rheumatic fever.
Yoo O, Salman S, Hla TK, Osowicki J, Page-Sharp M, Marsh JA, Barr R, Azzopardi K, Morici M, Batty KT, Enkel SL, Kado J, Hatchuel L, Fulurija A, McCarthy JS, Snelling T, Steer AC, Carapetis J, Manning L. Yoo O, et al. Among authors: mccarthy js. Antimicrob Agents Chemother. 2025 Jul 2;69(7):e0026925. doi: 10.1128/aac.00269-25. Epub 2025 May 20. Antimicrob Agents Chemother. 2025. PMID: 40391929 Free PMC article. Clinical Trial.
Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS): a randomised, double-blind, placebo-controlled trial.
Hla TK, Osowicki J, Marsh JA, Salman S, Page-Sharp M, Yoo O, Azzopardi K, Morici M, Batty KT, Barr RK, Enkel SL, Kado J, Hatchuel L, Fulurija A, McCarthy JS, Snelling TL, Steer AC, Carapetis J, Manning L. Hla TK, et al. Among authors: mccarthy js. Lancet Microbe. 2025 May;6(5):101038. doi: 10.1016/j.lanmic.2024.101038. Epub 2025 Mar 26. Lancet Microbe. 2025. PMID: 40157384 Free article. Clinical Trial.
Perceptions of a Buruli ulcer controlled human infection model: How, who, and why?
Muhi S, Schmidt S, Marshall JL, O'Brien DP, Johnson PDR, McCarthy JS, Jamrozik E, Osowicki J, Stinear TP. Muhi S, et al. Among authors: mccarthy js. PLoS Negl Trop Dis. 2025 Feb 5;19(2):e0012593. doi: 10.1371/journal.pntd.0012593. eCollection 2025 Feb. PLoS Negl Trop Dis. 2025. PMID: 39908304 Free PMC article.
321 results