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The 46-kDa mannose 6-phosphate receptor does not depend on endosomal acidification for delivery of hydrolases to lysosomes.

Probst OC, Ton P, Svoboda B, Gannon A, Schuhmann W, Wieser J, Pohlmann R, Mach L. Probst OC, et al. J Cell Sci. 2006 Dec 1;119(Pt 23):4935-43. doi: 10.1242/jcs.03283. Epub 2006 Nov 14. J Cell Sci. 2006. PMID: 17105763

Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis.

Schähs P, Weidinger P, Probst OC, Svoboda B, Stadlmann J, Beug H, Waerner T, Mach L. Schähs P, et al. Among authors: probst oc. Exp Cell Res. 2008 Oct 1;314(16):3036-47. doi: 10.1016/j.yexcr.2008.06.015. Epub 2008 Jun 28. Exp Cell Res. 2008. PMID: 18621046

The mannose 6-phosphate/insulin-like growth factor II receptor restricts the tumourigenicity and invasiveness of squamous cell carcinoma cells.

Probst OC, Puxbaum V, Svoboda B, Leksa V, Stockinger H, Mikula M, Mikulits W, Mach L. Probst OC, et al. Int J Cancer. 2009 Jun 1;124(11):2559-67. doi: 10.1002/ijc.24236. Int J Cancer. 2009. PMID: 19195023

The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells.

Probst OC, Karayel E, Schida N, Nimmerfall E, Hehenberger E, Puxbaum V, Mach L. Probst OC, et al. Biochem J. 2013 Apr 1;451(1):91-9. doi: 10.1042/BJ20121422. Biochem J. 2013. PMID: 23347038 Free PMC article.

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