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Haemophilia therapies.
Dargaud Y, Negrier C. Dargaud Y, et al. Among authors: negrier c. Expert Opin Biol Ther. 2007 May;7(5):651-63. doi: 10.1517/14712598.7.5.651. Expert Opin Biol Ther. 2007. PMID: 17477803 Review.
The safety and efficacy of recombinant human blood coagulation factor IX in previously untreated patients with severe or moderately severe hemophilia B.
Shapiro AD, Di Paola J, Cohen A, Pasi KJ, Heisel MA, Blanchette VS, Abshire TC, Hoots WK, Lusher JM, Negrier C, Rothschild C, Roth DA. Shapiro AD, et al. Among authors: negrier c. Blood. 2005 Jan 15;105(2):518-25. doi: 10.1182/blood-2004-06-2283. Epub 2004 Sep 21. Blood. 2005. PMID: 15383463 Free article. Clinical Trial.
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Sehgal A, Barros S, Ivanciu L, Cooley B, Qin J, Racie T, Hettinger J, Carioto M, Jiang Y, Brodsky J, Prabhala H, Zhang X, Attarwala H, Hutabarat R, Foster D, Milstein S, Charisse K, Kuchimanchi S, Maier MA, Nechev L, Kandasamy P, Kel'in AV, Nair JK, Rajeev KG, Manoharan M, Meyers R, Sorensen B, Simon AR, Dargaud Y, Negrier C, Camire RM, Akinc A. Sehgal A, et al. Among authors: negrier c. Nat Med. 2015 May;21(5):492-7. doi: 10.1038/nm.3847. Epub 2015 Apr 13. Nat Med. 2015. PMID: 25849132
293 results