A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels.
Tremblay F, Xiong Q, Shah SS, Ko CW, Kelly K, Morrison MS, Giancarlo C, Ramirez RN, Hildebrand EM, Voytek SB, El Sebae GK, Wright SH, Lofgren L, Clarkson S, Waters C, Linder SJ, Liu S, Eom T, Parikh S, Weber Y, Martinez S, Malyala P, Abubucker S, Friedland AE, Maeder ML, Lombardo A, Myer VE, Jaffe AB.
Tremblay F, et al. Among authors: morrison ms.
Nat Med. 2025 Apr;31(4):1329-1338. doi: 10.1038/s41591-025-03508-x. Epub 2025 Feb 10.
Nat Med. 2025.
PMID: 39930141
Free PMC article.