Markowitz JS - Search Results

1

Interactions of attention-deficit/hyperactivity disorder therapeutic agents with the efflux transporter P-glycoprotein.

Zhu HJ, Wang JS, Donovan JL, Jiang Y, Gibson BB, DeVane CL, Markowitz JS. Zhu HJ, et al. Among authors: markowitz js. Eur J Pharmacol. 2008 Jan 14;578(2-3):148-58. doi: 10.1016/j.ejphar.2007.09.035. Epub 2007 Oct 5. Eur J Pharmacol. 2008. PMID: 17963743 Free PMC article.

2

Sertraline and its metabolite desmethylsertraline, but not bupropion or its three major metabolites, have high affinity for P-glycoprotein.

Wang JS, Zhu HJ, Gibson BB, Markowitz JS, Donovan JL, DeVane CL. Wang JS, et al. Among authors: markowitz js. Biol Pharm Bull. 2008 Feb;31(2):231-4. doi: 10.1248/bpb.31.231. Biol Pharm Bull. 2008. PMID: 18239278 Free PMC article.

3

The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein.

Wang JS, Ruan Y, Taylor RM, Donovan JL, Markowitz JS, DeVane CL. Wang JS, et al. Among authors: markowitz js. Int J Neuropsychopharmacol. 2004 Dec;7(4):415-9. doi: 10.1017/S1461145704004390. Int J Neuropsychopharmacol. 2004. PMID: 15683552 Free article.

4

P-glycoprotein does not actively transport nicotine and cotinine.

Wang JS, Markowitz JS, Donovan JL, Devane CL. Wang JS, et al. Among authors: markowitz js. Addict Biol. 2005 Jun;10(2):127-9. doi: 10.1080/13556210500122995. Addict Biol. 2005. PMID: 16191663

5

Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana.

Zhu HJ, Wang JS, Markowitz JS, Donovan JL, Gibson BB, Gefroh HA, Devane CL. Zhu HJ, et al. Among authors: markowitz js. J Pharmacol Exp Ther. 2006 May;317(2):850-7. doi: 10.1124/jpet.105.098541. Epub 2006 Jan 26. J Pharmacol Exp Ther. 2006. PMID: 16439618

6

The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine.

Zhu HJ, Wang JS, DeVane CL, Williard RL, Donovan JL, Middaugh LD, Gibson BB, Patrick KS, Markowitz JS. Zhu HJ, et al. Among authors: markowitz js. Drug Metab Dispos. 2006 Jul;34(7):1116-21. doi: 10.1124/dmd.106.009605. Epub 2006 Apr 18. Drug Metab Dispos. 2006. PMID: 16621932

7

Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.

Wang JS, Zhu HJ, Markowitz JS, Donovan JL, DeVane CL. Wang JS, et al. Among authors: markowitz js. Psychopharmacology (Berl). 2006 Sep;187(4):415-23. doi: 10.1007/s00213-006-0437-9. Epub 2006 Jun 30. Psychopharmacology (Berl). 2006. PMID: 16810505

8

Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.

Zhu HJ, Wang JS, Markowitz JS, Donovan JL, Gibson BB, DeVane CL. Zhu HJ, et al. Among authors: markowitz js. Neuropsychopharmacology. 2007 Apr;32(4):757-64. doi: 10.1038/sj.npp.1301181. Epub 2006 Aug 23. Neuropsychopharmacology. 2007. PMID: 16936711 Free article.

9

Antipsychotic drugs inhibit the function of breast cancer resistance protein.

Wang JS, Zhu HJ, Markowitz JS, Donovan JL, Yuan HJ, Devane CL. Wang JS, et al. Among authors: markowitz js. Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):336-41. doi: 10.1111/j.1742-7843.2008.00298.x. Basic Clin Pharmacol Toxicol. 2008. PMID: 18834354 Free PMC article.

10

Aripiprazole brain concentration is altered in P-glycoprotein deficient mice.

Wang JS, Zhu HJ, Donovan JL, Yuan HJ, Markowitz JS, Geesey ME, Devane CL. Wang JS, et al. Among authors: markowitz js. Schizophr Res. 2009 May;110(1-3):90-4. doi: 10.1016/j.schres.2009.01.011. Epub 2009 Feb 23. Schizophr Res. 2009. PMID: 19239981

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