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Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.
Andersen ME, Black MB, Campbell JL, Pendse SN, Clewell HJ III, Pottenger LH, Bus JS, Dodd DE, Kemp DC, McMullen PD. Andersen ME, et al. Among authors: bus js. Toxicol Appl Pharmacol. 2017 Oct 1;332:149-158. doi: 10.1016/j.taap.2017.04.002. Epub 2017 Apr 7. Toxicol Appl Pharmacol. 2017. PMID: 28392392 Free article.
Response to the comments of Runyan et al. on "Trichloroethylene in drinking water throughout gestation did not produce congenital heart defects in Sprague Dawley rats".
DeSesso JM, Coder PS, York RG, Budinsky RA, Pottenger LH, Sen S, Lucarell JM, Bevan C, Bus JS. DeSesso JM, et al. Among authors: bus js. Birth Defects Res. 2019 Oct 1;111(16):1237-1239. doi: 10.1002/bdr2.1577. Epub 2019 Aug 16. Birth Defects Res. 2019. PMID: 31419071 Free article. No abstract available.
Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance.
Cruzan G, Bus JS, Banton MI, Sarang SS, Waites R, Layko DB, Raymond J, Dodd D, Andersen ME. Cruzan G, et al. Among authors: bus js. Toxicol Sci. 2017 Oct 1;159(2):413-421. doi: 10.1093/toxsci/kfx141. Toxicol Sci. 2017. PMID: 28962520 Free PMC article.
127 results