da Fonseca PC - Search Results

1

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P. Gyrd-Hansen M, et al. Among authors: da fonseca pc. Nat Cell Biol. 2008 Nov;10(11):1309-17. doi: 10.1038/ncb1789. Epub 2008 Oct 19. Nat Cell Biol. 2008. PMID: 18931663 Free PMC article.

2

Structural basis for the subunit assembly of the anaphase-promoting complex.

Schreiber A, Stengel F, Zhang Z, Enchev RI, Kong EH, Morris EP, Robinson CV, da Fonseca PC, Barford D. Schreiber A, et al. Among authors: da fonseca pc. Nature. 2011 Feb 10;470(7333):227-32. doi: 10.1038/nature09756. Nature. 2011. PMID: 21307936

3

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor.

da Fonseca PC, Kong EH, Zhang Z, Schreiber A, Williams MA, Morris EP, Barford D. da Fonseca PC, et al. Nature. 2011 Feb 10;470(7333):274-8. doi: 10.1038/nature09625. Epub 2010 Nov 24. Nature. 2011. PMID: 21107322 Free PMC article.

4

Molecular model of the human 26S proteasome.

da Fonseca PC, He J, Morris EP. da Fonseca PC, et al. Mol Cell. 2012 Apr 13;46(1):54-66. doi: 10.1016/j.molcel.2012.03.026. Mol Cell. 2012. PMID: 22500737 Free article.

5

Structure of the human 26S proteasome: subunit radial displacements open the gate into the proteolytic core.

da Fonseca PC, Morris EP. da Fonseca PC, et al. J Biol Chem. 2008 Aug 22;283(34):23305-14. doi: 10.1074/jbc.M802716200. Epub 2008 Jun 5. J Biol Chem. 2008. PMID: 18534977 Free PMC article.

6

Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy.

Govada L, Carpenter L, da Fonseca PC, Helliwell JR, Rizkallah P, Flashman E, Chayen NE, Redwood C, Squire JM. Govada L, et al. Among authors: da fonseca pc. J Mol Biol. 2008 Apr 25;378(2):387-97. doi: 10.1016/j.jmb.2008.02.044. Epub 2008 Mar 4. J Mol Biol. 2008. PMID: 18374358

7

Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).

Zhang Z, Yang J, Kong EH, Chao WC, Morris EP, da Fonseca PC, Barford D. Zhang Z, et al. Among authors: da fonseca pc. Biochem J. 2013 Jan 15;449(2):365-71. doi: 10.1042/BJ20121374. Biochem J. 2013. PMID: 23078409

8

The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric α-helical rings.

He J, Kulkarni K, da Fonseca PC, Krutauz D, Glickman MH, Barford D, Morris EP. He J, et al. Among authors: da fonseca pc. Structure. 2012 Mar 7;20(3):513-21. doi: 10.1016/j.str.2011.12.015. Structure. 2012. PMID: 22405010 Free article.

9

Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core.

da Fonseca PC, Morris EP. da Fonseca PC, et al. Nat Commun. 2015 Jul 2;6:7573. doi: 10.1038/ncomms8573. Nat Commun. 2015. PMID: 26133119 Free PMC article.

10

Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors.

Bhanumathy C, da Fonseca PC, Morris EP, Joseph SK. Bhanumathy C, et al. Among authors: da fonseca pc. J Biol Chem. 2012 Dec 21;287(52):43674-84. doi: 10.1074/jbc.M112.415786. Epub 2012 Oct 18. J Biol Chem. 2012. PMID: 23086950 Free PMC article.

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