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79 results

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Page 1
High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia.
Loriaux MM, Levine RL, Tyner JW, Fröhling S, Scholl C, Stoffregen EP, Wernig G, Erickson H, Eide CA, Berger R, Bernard OA, Griffin JD, Stone RM, Lee B, Meyerson M, Heinrich MC, Deininger MW, Gilliland DG, Druker BJ. Loriaux MM, et al. Blood. 2008 May 1;111(9):4788-96. doi: 10.1182/blood-2007-07-101394. Epub 2008 Feb 5. Blood. 2008. PMID: 18252861 Free PMC article.
RNAi screen for rapid therapeutic target identification in leukemia patients.
Tyner JW, Deininger MW, Loriaux MM, Chang BH, Gotlib JR, Willis SG, Erickson H, Kovacsovics T, O'Hare T, Heinrich MC, Druker BJ. Tyner JW, et al. Among authors: loriaux mm. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8695-700. doi: 10.1073/pnas.0903233106. Epub 2009 May 11. Proc Natl Acad Sci U S A. 2009. PMID: 19433805 Free PMC article.
A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib.
McWeeney SK, Pemberton LC, Loriaux MM, Vartanian K, Willis SG, Yochum G, Wilmot B, Turpaz Y, Pillai R, Druker BJ, Snead JL, MacPartlin M, O'Brien SG, Melo JV, Lange T, Harrington CA, Deininger MW. McWeeney SK, et al. Among authors: loriaux mm. Blood. 2010 Jan 14;115(2):315-25. doi: 10.1182/blood-2009-03-210732. Epub 2009 Oct 16. Blood. 2010. PMID: 19837975 Free PMC article.
MET receptor sequence variants R970C and T992I lack transforming capacity.
Tyner JW, Fletcher LB, Wang EQ, Yang WF, Rutenberg-Schoenberg ML, Beadling C, Mori M, Heinrich MC, Deininger MW, Druker BJ, Loriaux MM. Tyner JW, et al. Among authors: loriaux mm. Cancer Res. 2010 Aug 1;70(15):6233-7. doi: 10.1158/0008-5472.CAN-10-0429. Cancer Res. 2010. PMID: 20670955 Free PMC article.
TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.
Fleischman AG, Aichberger KJ, Luty SB, Bumm TG, Petersen CL, Doratotaj S, Vasudevan KB, LaTocha DH, Yang F, Press RD, Loriaux MM, Pahl HL, Silver RT, Agarwal A, O'Hare T, Druker BJ, Bagby GC, Deininger MW. Fleischman AG, et al. Among authors: loriaux mm. Blood. 2011 Dec 8;118(24):6392-8. doi: 10.1182/blood-2011-04-348144. Epub 2011 Aug 22. Blood. 2011. PMID: 21860020 Free PMC article.
BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.
Agarwal A, Mackenzie RJ, Besson A, Jeng S, Carey A, LaTocha DH, Fleischman AG, Duquesnes N, Eide CA, Vasudevan KB, Loriaux MM, Firpo E, Cortes JE, McWeeney S, O'Hare T, Roberts JM, Druker BJ, Deininger MW. Agarwal A, et al. Among authors: loriaux mm. Blood. 2014 Nov 20;124(22):3260-73. doi: 10.1182/blood-2013-04-497040. Epub 2014 Oct 7. Blood. 2014. PMID: 25293778 Free PMC article.
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia.
Levine RL, Loriaux M, Huntly BJ, Loh ML, Beran M, Stoffregen E, Berger R, Clark JJ, Willis SG, Nguyen KT, Flores NJ, Estey E, Gattermann N, Armstrong S, Look AT, Griffin JD, Bernard OA, Heinrich MC, Gilliland DG, Druker B, Deininger MW. Levine RL, et al. Blood. 2005 Nov 15;106(10):3377-9. doi: 10.1182/blood-2005-05-1898. Epub 2005 Aug 4. Blood. 2005. PMID: 16081687 Free PMC article. Clinical Trial.
79 results