Nemirovskiy OV - Search Results

1

Plasma 3-nitrotyrosine is a biomarker in animal models of arthritis: Pharmacological dissection of iNOS' role in disease.

Nemirovskiy OV, Radabaugh MR, Aggarwal P, Funckes-Shippy CL, Mnich SJ, Meyer DM, Sunyer T, Rodney Mathews W, Misko TP. Nemirovskiy OV, et al. Nitric Oxide. 2009 May;20(3):150-6. doi: 10.1016/j.niox.2008.12.005. Epub 2008 Dec 25. Nitric Oxide. 2009. PMID: 19146971

2

Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: development of a clinically translatable biomarker.

Radabaugh MR, Nemirovskiy OV, Misko TP, Aggarwal P, Mathews WR. Radabaugh MR, et al. Among authors: nemirovskiy ov. Anal Biochem. 2008 Sep 1;380(1):68-76. doi: 10.1016/j.ab.2008.05.019. Epub 2008 May 20. Anal Biochem. 2008. PMID: 18539125

3

Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis.

Nemirovskiy O, Zheng YJ, Tung D, Korniski B, Settle S, Skepner A, Yates M, Aggarwal P, Sunyer T, Aguiar DJ. Nemirovskiy O, et al. Xenobiotica. 2010 Aug;40(8):586-92. doi: 10.3109/00498254.2010.488303. Xenobiotica. 2010. PMID: 20509748

4

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis.

Nemirovskiy OV, Sunyer T, Aggarwal P, Abrams M, Hellio Le Graverand MP, Mathews WR. Nemirovskiy OV, et al. Osteoarthritis Cartilage. 2008 Dec;16(12):1494-500. doi: 10.1016/j.joca.2008.04.021. Epub 2008 Jun 16. Osteoarthritis Cartilage. 2008. PMID: 18556223 Free article.

5

Clinical validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide: A biomarker of matrix metalloproteinase activity and osteoarthritis in human urine.

Li WW, Nemirovskiy O, Fountain S, Rodney Mathews W, Szekely-Klepser G. Li WW, et al. Anal Biochem. 2007 Oct 1;369(1):41-53. doi: 10.1016/j.ab.2007.05.002. Epub 2007 May 6. Anal Biochem. 2007. PMID: 17570334

6

Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.

Mbalaviele G, Pauley AM, Shaffer AF, Zweifel BS, Mathialagan S, Mnich SJ, Nemirovskiy OV, Carter J, Gierse JK, Wang JL, Vazquez ML, Moore WM, Masferrer JL. Mbalaviele G, et al. Among authors: nemirovskiy ov. Biochem Pharmacol. 2010 May 15;79(10):1445-54. doi: 10.1016/j.bcp.2010.01.003. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067770

7

Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo.

Nemirovskiy OV, Dufield DR, Sunyer T, Aggarwal P, Welsch DJ, Mathews WR. Nemirovskiy OV, et al. Anal Biochem. 2007 Feb 1;361(1):93-101. doi: 10.1016/j.ab.2006.10.034. Epub 2006 Nov 15. Anal Biochem. 2007. PMID: 17187753

8

Cartilage degradation biomarkers predict efficacy of a novel, highly selective matrix metalloproteinase 13 inhibitor in a dog model of osteoarthritis: confirmation by multivariate analysis that modulation of type II collagen and aggrecan degradation peptides parallels pathologic changes.

Settle S, Vickery L, Nemirovskiy O, Vidmar T, Bendele A, Messing D, Ruminski P, Schnute M, Sunyer T. Settle S, et al. Arthritis Rheum. 2010 Oct;62(10):3006-15. doi: 10.1002/art.27596. Arthritis Rheum. 2010. PMID: 20533541

9

ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).

Zack MD, Malfait AM, Skepner AP, Yates MP, Griggs DW, Hall T, Hills RL, Alston JT, Nemirovskiy OV, Radabaugh MR, Leone JW, Arner EC, Tortorella MD. Zack MD, et al. Among authors: nemirovskiy ov. Arthritis Rheum. 2009 Sep;60(9):2704-13. doi: 10.1002/art.24753. Arthritis Rheum. 2009. PMID: 19714641

10

Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.

Rajagopalan LE, Davies MS, Kahn LE, Kornmeier CM, Shimada H, Steiner TA, Zweifel BS, Wendling JM, Payne MA, Loeffler RF, Case BL, Norton MB, Parikh MD, Nemirovskiy OV, Mourey RJ, Masferrer JL, Misko TP, Kolodziej SA. Rajagopalan LE, et al. Among authors: nemirovskiy ov. J Pharmacol Exp Ther. 2010 Jun;333(3):707-16. doi: 10.1124/jpet.110.166033. Epub 2010 Mar 12. J Pharmacol Exp Ther. 2010. PMID: 20228155

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