Hruby VJ - Search Results

1

Design and synthesis of highly potent and selective cyclic dynorphin A analogues.

Kawasaki AM, Knapp RJ, Kramer TH, Wire WS, Vasquez OS, Yamamura HI, Burks TF, Hruby VJ. Kawasaki AM, et al. Among authors: hruby vj. J Med Chem. 1990 Jul;33(7):1874-9. doi: 10.1021/jm00169a007. J Med Chem. 1990. PMID: 1972964

2

Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.

Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: hruby vj. J Med Chem. 2007 Jun 14;50(12):2779-86. doi: 10.1021/jm061369n. Epub 2007 May 22. J Med Chem. 2007. PMID: 17516639 Free PMC article.

3

Topographically designed analogues of [D-Pen,D-Pen5]enkephalin.

Hruby VJ, Toth G, Gehrig CA, Kao LF, Knapp R, Lui GK, Yamamura HI, Kramer TH, Davis P, Burks TF. Hruby VJ, et al. J Med Chem. 1991 Jun;34(6):1823-30. doi: 10.1021/jm00110a010. J Med Chem. 1991. PMID: 1648137

4

Delta opioid receptor-selective ligands: [D-Pen2,D-Pen5]enkephalin-dermenkephalin chimeric peptides.

Cavagnero S, Misicka A, Knapp RJ, Davis P, Fang L, Burks TF, Yamamura HI, Hruby VJ. Cavagnero S, et al. Among authors: hruby vj. Life Sci. 1991;49(7):495-503. doi: 10.1016/0024-3205(91)90066-k. Life Sci. 1991. PMID: 1650414

5

Topographical requirements for delta opioid ligands: presence of a carboxyl group in position 4 is not critical for deltorphin high delta receptor affinity and analgesic activity.

Misicka A, Lipkowski AW, Fang L, Knapp RJ, Davis P, Kramer T, Burks TF, Yamamura HI, Carr DB, Hruby VJ. Misicka A, et al. Among authors: hruby vj. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1290-7. doi: 10.1016/s0006-291x(05)81335-x. Biochem Biophys Res Commun. 1991. PMID: 1659410

6

Opioid receptor binding properties of analgesic analogues of cholecystokinin octapeptide.

Slaninova J, Knapp RJ, Wu JJ, Fang SN, Kramer T, Burks TF, Hruby VJ, Yamamura HI. Slaninova J, et al. Among authors: hruby vj. Eur J Pharmacol. 1991 Jul 23;200(1):195-8. doi: 10.1016/0014-2999(91)90688-m. Eur J Pharmacol. 1991. PMID: 1663041

7

[D-Pen2,D-Pen5]enkephalin analogues with increased affinity and selectivity for delta opioid receptors.

Toth G, Kramer TH, Knapp R, Lui G, Davis P, Burks TF, Yamamura HI, Hruby VJ. Toth G, et al. Among authors: hruby vj. J Med Chem. 1990 Jan;33(1):249-53. doi: 10.1021/jm00163a041. J Med Chem. 1990. PMID: 2153205

8

Cholecystokinin analogues with high affinity and selectivity for brain membrane receptors.

Hruby VJ, Fang SA, Knapp R, Kazmierski W, Lui GK, Yamamura HI. Hruby VJ, et al. Int J Pept Protein Res. 1990 Jun;35(6):566-73. doi: 10.1111/j.1399-3011.1990.tb00263.x. Int J Pept Protein Res. 1990. PMID: 2401597

9

Cholecystokinic activity of N alpha-hydroxysulfonyl-[Nle28,31]CCK26-33 analogues modified at the C-terminal residue.

Sugg EE, Serra M, Shook JE, Yamamura HI, Burks TF, Korc M, Hruby VJ. Sugg EE, et al. Among authors: hruby vj. Int J Pept Protein Res. 1988 Jun;31(6):514-9. doi: 10.1111/j.1399-3011.1988.tb00910.x. Int J Pept Protein Res. 1988. PMID: 2457563

10

Synthesis of highly mu and delta opioid receptor selective peptides containing a photoaffinity group.

Landis G, Lui G, Shook JE, Yamamura HI, Burks TF, Hruby VJ. Landis G, et al. Among authors: hruby vj. J Med Chem. 1989 Mar;32(3):638-43. doi: 10.1021/jm00123a023. J Med Chem. 1989. PMID: 2537426

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