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KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: gibbs a. Eur J Pharmacol. 2010 Apr 25;632(1-3):93-102. doi: 10.1016/j.ejphar.2010.01.011. Epub 2010 Feb 2. Eur J Pharmacol. 2010. PMID: 20132813
The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: gibbs a. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1772-7. doi: 10.1016/j.bmcl.2008.02.033. Epub 2008 Feb 16. Bioorg Med Chem Lett. 2008. PMID: 18325768
'Reverse' alpha-ketoamide-based p38 MAP kinase inhibitors.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ. Montalban AG, et al. Among authors: gibbs a. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5456-9. doi: 10.1016/j.bmcl.2008.09.028. Epub 2008 Sep 11. Bioorg Med Chem Lett. 2008. PMID: 18835164
Optimization of alpha-ketoamide based p38 inhibitors through modifications to the region that binds to the allosteric site.
Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Kucharski J, Lum C, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Urban J, Wang Z, Larson CJ. Montalban AG, et al. Among authors: gibbs a. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4819-24. doi: 10.1016/j.bmcl.2010.06.102. Bioorg Med Chem Lett. 2010. PMID: 20663667
Development and evaluation of a behaviour change intervention to increase general practitioner REferral of people with hip and knee osteoarthritis to community-based First-linE caRe (REFER): a mixed methods study.
Ezzat AM, Gibbs A, De Oliveira Silva D, Ferraz Pazzinatto M, Kemp JL, Manski-Nankervis J, Barton CJ. Ezzat AM, et al. Among authors: gibbs a. BMC Prim Care. 2025 Sep 26;26(1):291. doi: 10.1186/s12875-025-02968-x. BMC Prim Care. 2025. PMID: 41013210 Free PMC article.
940 results