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Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair.
Genschel J, Modrich P. Genschel J, et al. Among authors: modrich p. J Biol Chem. 2009 Aug 7;284(32):21536-44. doi: 10.1074/jbc.M109.021287. Epub 2009 Jun 10. J Biol Chem. 2009. PMID: 19515846 Free PMC article.
One model attributes the primary termination function in this system to RPA, with MutLalpha functioning in a secondary capacity by suppressing Exo1 hydrolysis of mismatch-free DNA (Genschel, J., and Modrich, P. (2003) Mol. Cell 12, 1077-1086). A second invokes MutLa …
One model attributes the primary termination function in this system to RPA, with MutLalpha functioning in a secondary capacity by suppressi …
Involvement of the beta clamp in methyl-directed mismatch repair in vitro.
Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Pluciennik A, et al. Among authors: modrich p. J Biol Chem. 2009 Nov 20;284(47):32782-91. doi: 10.1074/jbc.M109.054528. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783657 Free PMC article.
We have confirmed previous findings that beta clamp interacts specifically with MutS and MutL (Lopez de Saro, F. J., Marinus, M. G., Modrich, P., and O'Donnell, M. (2006) J. Biol. Chem. 281, 14340-14349) and show that the mutator phenotype conferred by amino acid su …
We have confirmed previous findings that beta clamp interacts specifically with MutS and MutL (Lopez de Saro, F. J., Marinus, M. G., Modr …
180 results