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The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein.
Loregian A, Mercorelli B, Muratore G, Sinigalia E, Pagni S, Massari S, Gribaudo G, Gatto B, Palumbo M, Tabarrini O, Cecchetti V, Palù G. Loregian A, et al. Among authors: cecchetti v. Antimicrob Agents Chemother. 2010 May;54(5):1930-40. doi: 10.1128/AAC.01730-09. Epub 2010 Mar 1. Antimicrob Agents Chemother. 2010. PMID: 20194695 Free PMC article.
In vitro activity of MF 5137, a new potent 6-aminoquinolone.
Wise R, Pagella PG, Cecchetti V, Fravolini A, Tabarrini O. Wise R, et al. Among authors: cecchetti v. Drugs. 1995;49 Suppl 2:272-3. doi: 10.2165/00003495-199500492-00067. Drugs. 1995. PMID: 8549329 No abstract available.
In vitro activities of new quinolones against Helicobacter pylori.
Carbone M, Fera MT, Cecchetti V, Tabarrini O, Losi E, Cusumano V, Teti G. Carbone M, et al. Among authors: cecchetti v. Antimicrob Agents Chemother. 1997 Dec;41(12):2790-2. doi: 10.1128/AAC.41.12.2790. Antimicrob Agents Chemother. 1997. PMID: 9420062 Free PMC article.
6-Aminoquinolones as new potential anti-HIV agents.
Cecchetti V, Parolin C, Moro S, Pecere T, Filipponi E, Calistri A, Tabarrini O, Gatto B, Palumbo M, Fravolini A, Palu' G. Cecchetti V, et al. J Med Chem. 2000 Oct 5;43(20):3799-802. doi: 10.1021/jm9903390. J Med Chem. 2000. PMID: 11020296
New anti-human immunodeficiency virus type 1 6-aminoquinolones: mechanism of action.
Parolin C, Gatto B, Del Vecchio C, Pecere T, Tramontano E, Cecchetti V, Fravolini A, Masiero S, Palumbo M, Palù G. Parolin C, et al. Among authors: cecchetti v. Antimicrob Agents Chemother. 2003 Mar;47(3):889-96. doi: 10.1128/AAC.47.3.889-896.2003. Antimicrob Agents Chemother. 2003. PMID: 12604517 Free PMC article.
A 6-aminoquinolone derivative, WM5, which bears a methyl substituent at the N-1 position and a 4-(2-pyridyl)-1-piperazine moiety at position 7 of the bicyclic quinolone ring system, was previously shown to exhibit potent activity against replication of human immunodeficiency viru …
A 6-aminoquinolone derivative, WM5, which bears a methyl substituent at the N-1 position and a 4-(2-pyridyl)-1-piperazine moiety at position …
154 results