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A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.
Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang YJ, Zhao XM, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung HC, Li XN. Yu L, et al. Among authors: perlaky l. Neuro Oncol. 2010 Jun;12(6):580-94. doi: 10.1093/neuonc/nop056. Epub 2010 Feb 8. Neuro Oncol. 2010. PMID: 20511191 Free PMC article.
A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models.
Yu L, Baxter PA, Zhao X, Liu Z, Wadhwa L, Zhang Y, Su JM, Tan X, Yang J, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Blaney SM, Chintagumpala M, Hurwitz RL, Li XN. Yu L, et al. Among authors: perlaky l. Neuro Oncol. 2011 Jan;13(1):14-27. doi: 10.1093/neuonc/noq148. Epub 2010 Nov 12. Neuro Oncol. 2011. PMID: 21075780 Free PMC article.
Intravenous injection of oncolytic picornavirus SVV-001 prolongs animal survival in a panel of primary tumor-based orthotopic xenograft mouse models of pediatric glioma.
Liu Z, Zhao X, Mao H, Baxter PA, Huang Y, Yu L, Wadhwa L, Su JM, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Hurwitz RL, Lau CC, Chintagumpala M, Blaney SM, Li XN. Liu Z, et al. Among authors: perlaky l. Neuro Oncol. 2013 Sep;15(9):1173-85. doi: 10.1093/neuonc/not065. Epub 2013 May 7. Neuro Oncol. 2013. PMID: 23658322 Free PMC article.
Direct Implantation of Patient Brain Tumor Cells into Matching Locations in Mouse Brains for Patient-Derived Orthotopic Xenograft Model Development.
Qi L, Baxter P, Kogiso M, Zhang H, Braun FK, Lindsay H, Zhao S, Xiao S, Abdallah AS, Suarez M, Huang Z, Teo WY, Yu L, Zhao X, Liu Z, Huang Y, Su JM, Man TK, Lau CC, Perlaky L, Du Y, Li XN. Qi L, et al. Among authors: perlaky l. Cancers (Basel). 2024 Apr 28;16(9):1716. doi: 10.3390/cancers16091716. Cancers (Basel). 2024. PMID: 38730671 Free PMC article.
Publisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas.
Zhao S, Li J, Zhang H, Qi L, Du Y, Kogiso M, Braun FK, Xiao S, Huang Y, Li J, Teo WY, Lindsay H, Baxter P, Su JMF, Adesina A, Laczik M, Genevini P, Veillard AC, Schvartzman S, Berguet G, Ding SR, Du L, Stephan C, Yang J, Davies PJA, Lu X, Chintagumpala M, Parsons DW, Perlaky L, Xia YF, Man TK, Huang Y, Sun D, Li XN. Zhao S, et al. Among authors: perlaky l. Nat Commun. 2022 Dec 22;13(1):7871. doi: 10.1038/s41467-022-35539-0. Nat Commun. 2022. PMID: 36550163 Free PMC article. No abstract available.
Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas.
Zhao S, Li J, Zhang H, Qi L, Du Y, Kogiso M, Braun FK, Xiao S, Huang Y, Li J, Teo WY, Lindsay H, Baxter P, Su JMF, Adesina A, Laczik M, Genevini P, Veillard AC, Schvartzman S, Berguet G, Ding SR, Du L, Stephan C, Yang J, Davies PJA, Lu X, Chintagumpala M, Parsons DW, Perlaky L, Xia YF, Man TK, Huang Y, Sun D, Li XN. Zhao S, et al. Among authors: perlaky l. Nat Commun. 2022 Nov 5;13(1):6689. doi: 10.1038/s41467-022-34514-z. Nat Commun. 2022. PMID: 36335125 Free PMC article.
Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma.
Kogiso M, Qi L, Du Y, Braun FK, Zhang H, Huang LF, Guo L, Huang Y, Teo WY, Lindsay H, Zhao S, Injac SG, Liu Z, Mehta V, Tran D, Li F, Baxter PA, Su JM, Perlaky L, Parsons DW, Chintagumpala M, Adesina A, Song Y, Li XN. Kogiso M, et al. Among authors: perlaky l. Transl Oncol. 2022 Apr;18:101368. doi: 10.1016/j.tranon.2022.101368. Epub 2022 Feb 16. Transl Oncol. 2022. PMID: 35182954 Free PMC article.
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.
Huang Y, Qi L, Kogiso M, Du Y, Braun FK, Zhang H, Huang LF, Xiao S, Teo WY, Lindsay H, Zhao S, Baxter P, Su JMF, Adesina A, Yang J, Brabetz S, Kool M, Pfister SM, Chintagumpala M, Perlaky L, Wang Z, Zhou Y, Man TK, Li XN. Huang Y, et al. Among authors: perlaky l. Adv Sci (Weinh). 2021 Dec;8(23):e2101923. doi: 10.1002/advs.202101923. Epub 2021 Nov 1. Adv Sci (Weinh). 2021. PMID: 34719887 Free PMC article.
Corrigendum to "Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors" [Cancer Lett. 493 (2020) 197-206].
Qi L, Kogiso M, Du Y, Zhang H, Braun FK, Huang Y, Teo WY, Lindsay H, Zhao S, Baxter P, Zhao X, Yu L, Liu Z, Zhang X, Su J, Adesina A, Yang J, Chintagumpala M, Perlaky L, Tsz-Kwong Man C, Lau CC, Li XN. Qi L, et al. Among authors: perlaky l. Cancer Lett. 2021 Mar 1;500:294. doi: 10.1016/j.canlet.2020.12.007. Epub 2020 Dec 23. Cancer Lett. 2021. PMID: 33358190 Free PMC article. No abstract available.
67 results