Handforth A - Search Results

1

T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor.

Handforth A, Homanics GE, Covey DF, Krishnan K, Lee JY, Sakimura K, Martin FC, Quesada A. Handforth A, et al. Neuropharmacology. 2010 Nov;59(6):380-7. doi: 10.1016/j.neuropharm.2010.05.012. Epub 2010 Jun 12. Neuropharmacology. 2010. PMID: 20547167 Free PMC article.

2

Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.

DeLorey TM, Handforth A, Anagnostaras SG, Homanics GE, Minassian BA, Asatourian A, Fanselow MS, Delgado-Escueta A, Ellison GD, Olsen RW. DeLorey TM, et al. Among authors: handforth a. J Neurosci. 1998 Oct 15;18(20):8505-14. doi: 10.1523/JNEUROSCI.18-20-08505.1998. J Neurosci. 1998. PMID: 9763493 Free PMC article.

3

Vagus nerve stimulation inhibits harmaline-induced tremor.

Krahl SE, Martin FC, Handforth A. Krahl SE, et al. Among authors: handforth a. Brain Res. 2004 Jun 11;1011(1):135-8. doi: 10.1016/j.brainres.2004.03.021. Brain Res. 2004. PMID: 15140653

4

Pilot efficacy and tolerability: a randomized, placebo-controlled trial of levetiracetam for essential tremor.

Handforth A, Martin FC. Handforth A, et al. Mov Disord. 2004 Oct;19(10):1215-21. doi: 10.1002/mds.20147. Mov Disord. 2004. PMID: 15390011 Clinical Trial.

5

Harmaline-induced tremor as a potential preclinical screening method for essential tremor medications.

Martin FC, Thu Le A, Handforth A. Martin FC, et al. Among authors: handforth a. Mov Disord. 2005 Mar;20(3):298-305. doi: 10.1002/mds.20331. Mov Disord. 2005. PMID: 15580562

6

GABAA receptor beta3 subunit gene-deficient heterozygous mice show parent-of-origin and gender-related differences in beta3 subunit levels, EEG, and behavior.

Liljelund P, Handforth A, Homanics GE, Olsen RW. Liljelund P, et al. Among authors: handforth a. Brain Res Dev Brain Res. 2005 Jun 30;157(2):150-61. doi: 10.1016/j.devbrainres.2005.03.014. Brain Res Dev Brain Res. 2005. PMID: 15878204

7

Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.

Handforth A, Delorey TM, Homanics GE, Olsen RW. Handforth A, et al. Epilepsia. 2005 Dec;46(12):1860-70. doi: 10.1111/j.1528-1167.2005.00287.x. Epilepsia. 2005. PMID: 16393151

8

Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor.

Martin FC, Handforth A. Martin FC, et al. Among authors: handforth a. Mov Disord. 2006 Oct;21(10):1641-9. doi: 10.1002/mds.20940. Mov Disord. 2006. PMID: 16773639

9

The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil.

Bui PH, Quesada A, Handforth A, Hankinson O. Bui PH, et al. Among authors: handforth a. Drug Metab Dispos. 2008 Jul;36(7):1291-9. doi: 10.1124/dmd.107.020115. Epub 2008 Apr 14. Drug Metab Dispos. 2008. PMID: 18411403 Free PMC article.

10

Zonisamide for essential tremor: an evaluator-blinded study.

Handforth A, Martin FC, Kang GA, Vanek Z. Handforth A, et al. Mov Disord. 2009 Feb 15;24(3):437-40. doi: 10.1002/mds.22418. Mov Disord. 2009. PMID: 19117357

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