Miller DS - Search Results

1

Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.

Wang X, Hawkins BT, Miller DS. Wang X, et al. Among authors: miller ds. FASEB J. 2011 Feb;25(2):644-52. doi: 10.1096/fj.10-169227. Epub 2010 Nov 3. FASEB J. 2011. PMID: 21048045 Free PMC article.

2

Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor.

Hawkins BT, Sykes DB, Miller DS. Hawkins BT, et al. Among authors: miller ds. J Neurosci. 2010 Jan 27;30(4):1417-25. doi: 10.1523/JNEUROSCI.5103-09.2010. J Neurosci. 2010. PMID: 20107068 Free PMC article.

3

Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain.

Rigor RR, Hawkins BT, Miller DS. Rigor RR, et al. Among authors: miller ds. J Cereb Blood Flow Metab. 2010 Jul;30(7):1373-83. doi: 10.1038/jcbfm.2010.21. Epub 2010 Mar 3. J Cereb Blood Flow Metab. 2010. PMID: 20197783 Free PMC article.

4

Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.

Wang X, Sykes DB, Miller DS. Wang X, et al. Among authors: miller ds. Mol Pharmacol. 2010 Sep;78(3):376-83. doi: 10.1124/mol.110.063685. Epub 2010 Jun 14. Mol Pharmacol. 2010. PMID: 20547735 Free PMC article.

5

Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay.

Hawkins BT, Rigor RR, Miller DS. Hawkins BT, et al. Among authors: miller ds. J Cereb Blood Flow Metab. 2010 Sep;30(9):1593-7. doi: 10.1038/jcbfm.2010.117. Epub 2010 Jul 14. J Cereb Blood Flow Metab. 2010. PMID: 20628400 Free PMC article.

6

Activating PKC-β1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS.

Wang X, Hawkins BT, Miller DS. Wang X, et al. Among authors: miller ds. J Cereb Blood Flow Metab. 2011 Jun;31(6):1371-5. doi: 10.1038/jcbfm.2011.44. Epub 2011 Apr 13. J Cereb Blood Flow Metab. 2011. PMID: 21487415 Free PMC article.

7

ABC transporter function and regulation at the blood-spinal cord barrier.

Campos CR, Schröter C, Wang X, Miller DS. Campos CR, et al. Among authors: miller ds. J Cereb Blood Flow Metab. 2012 Aug;32(8):1559-66. doi: 10.1038/jcbfm.2012.47. Epub 2012 Apr 4. J Cereb Blood Flow Metab. 2012. PMID: 22472606 Free PMC article.

8

Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain.

Cannon RE, Peart JC, Hawkins BT, Campos CR, Miller DS. Cannon RE, et al. Among authors: miller ds. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15930-5. doi: 10.1073/pnas.1203534109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949658 Free PMC article.

9

Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.

Wang X, Cabrera RM, Li Y, Miller DS, Finnell RH. Wang X, et al. Among authors: miller ds. FASEB J. 2013 Mar;27(3):1167-75. doi: 10.1096/fj.12-218495. Epub 2012 Dec 4. FASEB J. 2013. PMID: 23212123 Free PMC article.

10

Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers.

Wang X, Campos CR, Peart JC, Smith LK, Boni JL, Cannon RE, Miller DS. Wang X, et al. Among authors: miller ds. J Neurosci. 2014 Jun 18;34(25):8585-93. doi: 10.1523/JNEUROSCI.2935-13.2014. J Neurosci. 2014. PMID: 24948812 Free PMC article.

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