Spring DR - Search Results

1

Rational methods for the selection of diverse screening compounds.

Huggins DJ, Venkitaraman AR, Spring DR. Huggins DJ, et al. Among authors: spring dr. ACS Chem Biol. 2011 Mar 18;6(3):208-17. doi: 10.1021/cb100420r. Epub 2011 Feb 15. ACS Chem Biol. 2011. PMID: 21261294 Free PMC article. Review.

2

Small-molecule screening: advances in microarraying and cell-imaging technologies.

Nicholson RL, Welch M, Ladlow M, Spring DR. Nicholson RL, et al. Among authors: spring dr. ACS Chem Biol. 2007 Jan 23;2(1):24-30. doi: 10.1021/cb600321j. ACS Chem Biol. 2007. PMID: 17243780 Review.

3

Learning the language of bacteria.

Hodgkinson JT, Welch M, Spring DR. Hodgkinson JT, et al. Among authors: spring dr. ACS Chem Biol. 2007 Nov 20;2(11):715-7. doi: 10.1021/cb700227k. ACS Chem Biol. 2007. PMID: 18030987 Review.

4

The discovery of antibacterial agents using diversity-oriented synthesis.

Galloway WR, Bender A, Welch M, Spring DR. Galloway WR, et al. Among authors: spring dr. Chem Commun (Camb). 2009 May 14;(18):2446-62. doi: 10.1039/b816852k. Epub 2009 Apr 1. Chem Commun (Camb). 2009. PMID: 19532856 Review.

5

Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity.

Zheng S, Laraia L, O' Connor CJ, Sorrell D, Tan YS, Xu Z, Venkitaraman AR, Wu W, Spring DR. Zheng S, et al. Among authors: spring dr. Org Biomol Chem. 2012 Apr 7;10(13):2590-3. doi: 10.1039/c2ob25065a. Epub 2012 Feb 23. Org Biomol Chem. 2012. PMID: 22361895

6

Diversity-oriented synthesis: producing chemical tools for dissecting biology.

O' Connor CJ, Beckmann HS, Spring DR. O' Connor CJ, et al. Among authors: spring dr. Chem Soc Rev. 2012 Jun 21;41(12):4444-56. doi: 10.1039/c2cs35023h. Epub 2012 Apr 10. Chem Soc Rev. 2012. PMID: 22491328 Review.

7

Palladium-catalysed cross-coupling of vinyldisiloxanes with benzylic and allylic halides and sulfonates.

Frye EC, O'Connor CJ, Twigg DG, Elbert B, Laraia L, Hulcoop DG, Venkitaraman AR, Spring DR. Frye EC, et al. Among authors: spring dr. Chemistry. 2012 Jul 9;18(28):8774-9. doi: 10.1002/chem.201200431. Epub 2012 Jun 8. Chemistry. 2012. PMID: 22678946

8

A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.

O'Connell KM, Beckmann HS, Laraia L, Horsley HT, Bender A, Venkitaraman AR, Spring DR. O'Connell KM, et al. Among authors: spring dr. Org Biomol Chem. 2012 Oct 7;10(37):7545-51. doi: 10.1039/c2ob26272j. Org Biomol Chem. 2012. PMID: 22890306

9

How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.

Koutsoukas A, Paricharak S, Galloway WR, Spring DR, Ijzerman AP, Glen RC, Marcus D, Bender A. Koutsoukas A, et al. Among authors: spring dr. J Chem Inf Model. 2014 Jan 27;54(1):230-42. doi: 10.1021/ci400469u. Epub 2013 Dec 13. J Chem Inf Model. 2014. PMID: 24289493

10

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.

Ibbeson BM, Laraia L, Alza E, O' Connor CJ, Tan YS, Davies HM, McKenzie G, Venkitaraman AR, Spring DR. Ibbeson BM, et al. Among authors: spring dr. Nat Commun. 2014;5:3155. doi: 10.1038/ncomms4155. Nat Commun. 2014. PMID: 24434687 Free article.

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