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5,157 results

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Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington's Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits.
Kudwa AE, Menalled LB, Oakeshott S, Murphy C, Mushlin R, Fitzpatrick J, Miller SF, McConnell K, Port R, Torello J, Howland D, Ramboz S, Brunner D. Kudwa AE, et al. Among authors: murphy c. PLoS Curr. 2013 Jul 30;5:ecurrents.hd.0ab4f3645aff523c56ecc8ccbe41a198. doi: 10.1371/currents.hd.0ab4f3645aff523c56ecc8ccbe41a198. PLoS Curr. 2013. PMID: 24042107 Free PMC article.
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Menalled LB, Kudwa AE, Miller S, Fitzpatrick J, Watson-Johnson J, Keating N, Ruiz M, Mushlin R, Alosio W, McConnell K, Connor D, Murphy C, Oakeshott S, Kwan M, Beltran J, Ghavami A, Brunner D, Park LC, Ramboz S, Howland D. Menalled LB, et al. Among authors: murphy c. PLoS One. 2012;7(12):e49838. doi: 10.1371/journal.pone.0049838. Epub 2012 Dec 20. PLoS One. 2012. PMID: 23284626 Free PMC article.
The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease.
Beaumont V, Park L, Rassoulpour A, Dijkman U, Heikkinen T, Lehtimaki K, Kontkanen O, Al Nackkash R, Bates GP, Gleyzes M, Steidl E, Ramboz S, Murphy C, Beconi MG, Dominguez C, Munoz-Sanjuan I. Beaumont V, et al. Among authors: murphy c. PLoS Curr. 2014 Feb 13;6:ecurrents.hd.3304e87e460b4bb0dc519a29f4deccca. doi: 10.1371/currents.hd.3304e87e460b4bb0dc519a29f4deccca. PLoS Curr. 2014. PMID: 24558637 Free PMC article.
A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease.
Smith MR, Syed A, Lukacsovich T, Purcell J, Barbaro BA, Worthge SA, Wei SR, Pollio G, Magnoni L, Scali C, Massai L, Franceschini D, Camarri M, Gianfriddo M, Diodato E, Thomas R, Gokce O, Tabrizi SJ, Caricasole A, Landwehrmeyer B, Menalled L, Murphy C, Ramboz S, Luthi-Carter R, Westerberg G, Marsh JL. Smith MR, et al. Among authors: murphy c. Hum Mol Genet. 2014 Jun 1;23(11):2995-3007. doi: 10.1093/hmg/ddu010. Epub 2014 Jan 16. Hum Mol Genet. 2014. PMID: 24436303 Free PMC article.
Estimates of SARS-CoV-2 vaccine effectiveness against COVID-19-associated hospitalisation in paediatric patients in Hong Kong during two successive SARS-CoV-2 epidemic waves dominated by the Omicron variant: A test-negative design study.
Okoli GN, Kwan MYW, Chan ELY, Murphy C, Wong JSC, Chua H, Peiris M, Cowling BJ, Lee SL. Okoli GN, et al. Among authors: murphy c. Vaccine. 2026 Jan 23;75:128262. doi: 10.1016/j.vaccine.2026.128262. Online ahead of print. Vaccine. 2026. PMID: 41579753
Long-term outcomes of abatacept in individuals at risk of developing rheumatoid arthritis (ALTO): a randomised, double-blind, placebo-controlled trial.
Cope AP, Jasenecova M, Vasconcelos JC, Qureshi S, van Schie KA, Filer A, Raza K, D'Agostino MA, McInnes IB, Siebert S, Isaacs JD, Pratt AG, Fisher BA, Buckley CD, Emery P, Mankia K, Ho P, Buch MH, Ciurtin C, van Schaardenburg D, Huizinga TWJ, Toes REM, Georgiou E, Kelly J, Murphy C, Prevost AT; ALTO Study Investigators. Cope AP, et al. Among authors: murphy c. Lancet Rheumatol. 2026 Jan 20:S2665-9913(25)00371-6. doi: 10.1016/S2665-9913(25)00371-6. Online ahead of print. Lancet Rheumatol. 2026. PMID: 41576971 Free article.
5,157 results