Heximer SP - Search Results

1

Iron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation.

Rose RA, Sellan M, Simpson JA, Izaddoustdar F, Cifelli C, Panama BK, Davis M, Zhao D, Markhani M, Murphy GG, Striessnig J, Liu PP, Heximer SP, Backx PH. Rose RA, et al. Among authors: heximer sp. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):733-42. doi: 10.1161/CIRCEP.110.960401. Epub 2011 Jul 11. Circ Arrhythm Electrophysiol. 2011. PMID: 21747058 Free PMC article.

2

RGS4 regulates parasympathetic signaling and heart rate control in the sinoatrial node.

Cifelli C, Rose RA, Zhang H, Voigtlaender-Bolz J, Bolz SS, Backx PH, Heximer SP. Cifelli C, et al. Among authors: heximer sp. Circ Res. 2008 Aug 29;103(5):527-35. doi: 10.1161/CIRCRESAHA.108.180984. Epub 2008 Jul 24. Circ Res. 2008. PMID: 18658048 Free article.

3

RGS proteins: identifying new GAPs in the understanding of blood pressure regulation and cardiovascular function.

Gu S, Cifelli C, Wang S, Heximer SP. Gu S, et al. Among authors: heximer sp. Clin Sci (Lond). 2009 Mar;116(5):391-9. doi: 10.1042/CS20080272. Clin Sci (Lond). 2009. PMID: 19175357 Review.

4

Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse.

Pacey LK, Doss L, Cifelli C, van der Kooy D, Heximer SP, Hampson DR. Pacey LK, et al. Among authors: heximer sp. Mol Cell Neurosci. 2011 Mar;46(3):563-72. doi: 10.1016/j.mcn.2010.12.005. Epub 2011 Jan 6. Mol Cell Neurosci. 2011. PMID: 21215802

5

The primary benefits of angiotensin-converting enzyme inhibition on cardiac remodeling occur during sleep time in murine pressure overload hypertrophy.

Martino TA, Tata N, Simpson JA, Vanderlaan R, Dawood F, Kabir MG, Khaper N, Cifelli C, Podobed P, Liu PP, Husain M, Heximer S, Backx PH, Sole MJ. Martino TA, et al. J Am Coll Cardiol. 2011 May 17;57(20):2020-8. doi: 10.1016/j.jacc.2010.11.022. J Am Coll Cardiol. 2011. PMID: 21565639 Free article.

6

L-tryptophan ethyl ester dilates small mesenteric arteries by inhibition of voltage-operated calcium channels in smooth muscle.

Jadhav A, Liang W, Balsevich J, Bastin G, Kroetsch J, Heximer S, Backx PH, Gopalakrishnan V. Jadhav A, et al. Br J Pharmacol. 2012 May;166(1):232-42. doi: 10.1111/j.1476-5381.2011.01693.x. Br J Pharmacol. 2012. PMID: 21951131 Free PMC article.

7

Origin-specific epigenetic program correlates with vascular bed-specific differences in Rgs5 expression.

Zhang H, Gu S, Al-Sabeq B, Wang S, He J, Tam A, Cifelli C, Mathalone N, Tirgari S, Boyd S, Heximer SP. Zhang H, et al. Among authors: heximer sp. FASEB J. 2012 Jan;26(1):181-91. doi: 10.1096/fj.11-185454. Epub 2011 Sep 29. FASEB J. 2012. PMID: 21965603

8

Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure.

Meissner A, Yang J, Kroetsch JT, Sauvé M, Dax H, Momen A, Noyan-Ashraf MH, Heximer S, Husain M, Lidington D, Bolz SS. Meissner A, et al. Circulation. 2012 Jun 5;125(22):2739-50. doi: 10.1161/CIRCULATIONAHA.111.047316. Epub 2012 Apr 25. Circulation. 2012. PMID: 22534621

9

Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling.

Yang J, Noyan-Ashraf MH, Meissner A, Voigtlaender-Bolz J, Kroetsch JT, Foltz W, Jaffray D, Kapoor A, Momen A, Heximer SP, Zhang H, van Eede M, Henkelman RM, Matthews SG, Lidington D, Husain M, Bolz SS. Yang J, et al. Among authors: heximer sp. Circulation. 2012 Jul 10;126(2):196-206. doi: 10.1161/CIRCULATIONAHA.111.039644. Epub 2012 Jun 5. Circulation. 2012. PMID: 22668972

10

Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes.

Jadhav A, Liang W, Papageorgiou PC, Shoker A, Kanthan SC, Balsevich J, Levy AS, Heximer S, Backx PH, Gopalakrishnan V. Jadhav A, et al. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. doi: 10.1124/jpet.112.199661. Epub 2013 Mar 26. J Pharmacol Exp Ther. 2013. PMID: 23532933

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