Fleming JS - Search Results

1

Octimibate inhibition of platelet aggregation: stimulation of adenylate cyclase through prostacyclin receptor activation.

Seiler S, Brassard CL, Arnold AJ, Meanwell NA, Fleming JS, Keely SL Jr. Seiler S, et al. Among authors: fleming js. J Pharmacol Exp Ther. 1990 Dec;255(3):1021-6. J Pharmacol Exp Ther. 1990. PMID: 2175792

2

Structure-activity relationships associated with 3,4,5-triphenyl-1H-pyrazole-1-nonanoic acid, a nonprostanoid prostacyclin mimetic.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Seiler SM. Meanwell NA, et al. Among authors: fleming js. J Med Chem. 1992 Jan 24;35(2):389-97. doi: 10.1021/jm00080a028. J Med Chem. 1992. PMID: 1370696

3

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.

Meanwell NA, Rosenfeld MJ, Trehan AK, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Zavoico GB, et al. Meanwell NA, et al. Among authors: fleming js. J Med Chem. 1992 Sep 18;35(19):3483-97. doi: 10.1021/jm00097a006. J Med Chem. 1992. PMID: 1404230

4

Nonprostanoid prostacyclin mimetics. 3. Structural variations of the diphenyl heterocycle moiety.

Meanwell NA, Rosenfeld MJ, Trehan AK, Romine JL, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, et al. Meanwell NA, et al. Among authors: fleming js. J Med Chem. 1992 Sep 18;35(19):3498-512. doi: 10.1021/jm00097a007. J Med Chem. 1992. PMID: 1404231

5

Imidazoquinoline derivatives: potent inhibitors of platelet cAMP phosphodiesterase which elevate cAMP levels and activate protein kinase in platelets.

Seiler S, Gillespie E, Arnold AJ, Brassard CL, Meanwell NA, Fleming JS. Seiler S, et al. Among authors: fleming js. Thromb Res. 1991 Apr;62(1-2):31-42. doi: 10.1016/0049-3848(91)90666-k. Thromb Res. 1991. PMID: 1649498

6

1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

Meanwell NA, Roth HR, Smith EC, Wedding DL, Wright JJ, Fleming JS, Gillespie E. Meanwell NA, et al. Among authors: fleming js. J Med Chem. 1991 Sep;34(9):2906-16. doi: 10.1021/jm00113a033. J Med Chem. 1991. PMID: 1654430

7

Pharmacology of a potent, new antithrombotic agent, 1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one (BMY-20844).

Buchanan JO, Fleming JS, Cornish BT, Baryla UM, Gillespie E, Stanton HC, Seiler SM, Keely SL. Buchanan JO, et al. Among authors: fleming js. Thromb Res. 1989 Nov 1;56(3):333-46. doi: 10.1016/0049-3848(89)90246-6. Thromb Res. 1989. PMID: 2559492

8

2-[3-[2-(4,5-Diphenyl-2-oxazolyl) ethyl] phenoxy] acetic acid (BMY 42393): a new, structurally-novel prostacyclin partial agonist: 1). Inhibition of platelet aggregation and mechanism of action.

Seiler SM, Brassard CL, Federici ME, Buchanan JO, Zavoico GB, Fleming JS, Meanwell NA. Seiler SM, et al. Among authors: fleming js. Thromb Res. 1994 Apr 15;74(2):115-23. doi: 10.1016/0049-3848(94)90004-3. Thromb Res. 1994. PMID: 8029812

9

Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted alpha to the oxazole ring.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Hartl KS, Zavoico GB, et al. Meanwell NA, et al. Among authors: fleming js. J Med Chem. 1993 Nov 26;36(24):3871-83. doi: 10.1021/jm00076a017. J Med Chem. 1993. PMID: 8254619

10

Antithrombotic activity of BMY-43351, a new imidazoquinoline with enhanced aqueous solubility.

Fleming JS, Buchanan JO, Seiler SM, Meanwell NA. Fleming JS, et al. Thromb Res. 1991 Jul 1;63(1):145-55. doi: 10.1016/0049-3848(91)90277-4. Thromb Res. 1991. PMID: 1948816

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