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Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions.
Gesing A, Masternak MM, Wang F, Joseph AM, Leeuwenburgh C, Westbrook R, Lewinski A, Karbownik-Lewinska M, Bartke A. Gesing A, et al. Among authors: leeuwenburgh c. J Gerontol A Biol Sci Med Sci. 2011 Oct;66(10):1062-76. doi: 10.1093/gerona/glr080. Epub 2011 Jul 25. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21788651 Free PMC article.
The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals.
Joseph AM, Adhihetty PJ, Buford TW, Wohlgemuth SE, Lees HA, Nguyen LM, Aranda JM, Sandesara BD, Pahor M, Manini TM, Marzetti E, Leeuwenburgh C. Joseph AM, et al. Among authors: leeuwenburgh c. Aging Cell. 2012 Oct;11(5):801-9. doi: 10.1111/j.1474-9726.2012.00844.x. Epub 2012 Jul 9. Aging Cell. 2012. PMID: 22681576 Free PMC article.
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy.
Calvani R, Joseph AM, Adhihetty PJ, Miccheli A, Bossola M, Leeuwenburgh C, Bernabei R, Marzetti E. Calvani R, et al. Among authors: leeuwenburgh c. Biol Chem. 2013 Mar;394(3):393-414. doi: 10.1515/hsz-2012-0247. Biol Chem. 2013. PMID: 23154422 Free PMC article. Review.
Short-term caloric restriction, resveratrol, or combined treatment regimens initiated in late-life alter mitochondrial protein expression profiles in a fiber-type specific manner in aged animals.
Joseph AM, Malamo AG, Silvestre J, Wawrzyniak N, Carey-Love S, Nguyen LM, Dutta D, Xu J, Leeuwenburgh C, Adhihetty PJ. Joseph AM, et al. Among authors: leeuwenburgh c. Exp Gerontol. 2013 Sep;48(9):858-68. doi: 10.1016/j.exger.2013.05.061. Epub 2013 Jun 7. Exp Gerontol. 2013. PMID: 23747682 Free PMC article.
369 results