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Page 1
Spirometry thresholds for clinical trial eligibility: time for urgent re-evaluation.
Bokobza I, Le Sayec M, Bossley C, Brugha R, Davies JC, Dawson C, Holt L, Hughes DA, Needham Y, Pao C, Ruiz G, Safavi S, Saunders C, Shafi N, Simmonds NJ, Waller MD, Watson D, Davies G. Bokobza I, et al. Among authors: simmonds nj. Thorax. 2025 Oct 15;80(11):849-852. doi: 10.1136/thorax-2024-222652. Thorax. 2025. PMID: 40908142 Free PMC article.
Maximising opportunity for therapeutic success: sequential participation in cystic fibrosis nucleic acid-based therapy trials.
Mayer-Hamblett N, Kerper NR, Clancy JP, Davies JC, Taylor-Cousar JL, Donaldson SH, Bell SC, Jain R, Simmonds NJ, Mall MA, Goss CH, Rayment JH, Setiawan L, Pilewski JM. Mayer-Hamblett N, et al. Among authors: simmonds nj. Lancet Respir Med. 2025 Dec;13(12):1108-1118. doi: 10.1016/S2213-2600(25)00206-1. Epub 2025 Jul 30. Lancet Respir Med. 2025. PMID: 40752498 Review.
Evaluation of a national digital pre-implantation biopsy service for deceased-donor kidney transplantation in the UK (Pithia trial); a stepped-wedge cluster randomised registry trial.
Summers DM, Ayorinde JOO, Neil DA, Hemming K, Smith L, Mehew J, Thomas H, Brown R, Phillips S, Laing E, Sidders A, Deary AJ, Johnson RJ, Bardsley V, Thiru S, Griffiths MH, Perera R, Cain O, Roufosse C, Simmonds N, Sheaff M, Brearley N, Vydianath B, Paterson A, Gopalakrishnan K, Chatzitolios A, Callaghan CJ, Jarvis R, Dor FJMF, Dutta S, Bagul A, Wilson C, Ridgway D, Barlow A, Baker R, Sharif A, McDaid J, Terrace J, Marson L, Roy D, Hunter J, Szabo L, Knight S, Stevenson K, Mark P, Turner S, Moinuddin Z, Ghazanfar A, Sivaprakasam R, Motallebzadeh R, Torpey N, Jones G, Boffa C, Gibbs P, Connor A, Saif I, Shrestha B, Hill H, Fotheringham J, Pettigrew GJ. Summers DM, et al. Among authors: simmonds n. Lancet Reg Health Eur. 2025 Jul 22;56:101390. doi: 10.1016/j.lanepe.2025.101390. eCollection 2025 Sep. Lancet Reg Health Eur. 2025. PMID: 40735376 Free PMC article.
Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosis.
Uden A, Dunsche I, Janciauskiene S, Gräber S, Feng L, Tamm S, Hedtfeld S, Stege G, Jahn K, Kontsendorn J, Alfeis N, Kühbandner I, Minso R, Dopfer C, Griese M, Sommerburg O, Ringshausen FC, Nährlich L, Hansen G, Welte T, Braubach P, Mall MA, Tümmler B, Dittrich AM, Stanke F; CF teams from the European CF Twin and Sibling Study. Uden A, et al. EBioMedicine. 2025 Aug;118:105848. doi: 10.1016/j.ebiom.2025.105848. Epub 2025 Jul 10. EBioMedicine. 2025. PMID: 40645008 Free PMC article.
A standard operating procedure for reducing risk from medications prohibited during clinical trials in cystic fibrosis.
Sayec ML, Davies G, Waller MD, Davies JC, Simmonds NJ, Jones A, Brugha R, Dawson C, Macedo P, Ruiz G, Hughes D, Shah V, Pao C, Shafi N, Brown S, Watson D, Baker L, Lillis A, Ruffles T, Needham Y, Safavi S, Bokobza I, Holt L, Longmate J, Sketchley S, Cameron L, Bossley CJ. Sayec ML, et al. Among authors: simmonds nj. J Cyst Fibros. 2025 Jul;24(4):667-668. doi: 10.1016/j.jcf.2025.05.007. Epub 2025 Jun 9. J Cyst Fibros. 2025. PMID: 40494748 No abstract available.
Managing an ageing cystic fibrosis population: challenges and priorities.
Frost FJ, Peckham DG, Felton IC, Snowball JE, Gray RD, Jones AM, Simmonds NJ, Lord RW, Lip GYH, Chandler H, Murphy K, Downey DG, Sheppard DN, Davies JC, Bull J, Sommer P, Cupid B, Allen L, Duckers J. Frost FJ, et al. Among authors: simmonds nj. Eur Respir Rev. 2025 May 14;34(176):240261. doi: 10.1183/16000617.0261-2024. Print 2025 Apr. Eur Respir Rev. 2025. PMID: 40368426 Free PMC article. Review.
Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project.
Cheong J, Boreland S, Shattock E, Bowman E, Belkarty B, Jones A, Felton I, Ukor EF, Stowell J, Jose RJ, Madge S, Wilkins J, Frost E, Premachandra P, Loebinger M, Simmonds NJ, Drobniewski F, Shah A. Cheong J, et al. Among authors: simmonds nj. BMJ Open Qual. 2025 Apr 15;14(2):e002847. doi: 10.1136/bmjoq-2024-002847. BMJ Open Qual. 2025. PMID: 40233985 Free PMC article.
159 results